Results 51 to 60 of about 229,737 (177)

Evaluation of therapeutic effects of D‐limonene following orchiopexy in the rat model of cryptorchidism

Animal Models and Experimental Medicine, EarlyView.
D‐limonene supplementation enhances testicular recovery following orchiopexy in a rat model of bilateral cryptorchidism. Treatment with D‐limonene reduces oxidative stress (↓MDA, ↑SOD, ↑GPx, ↑TAC), downregulates pro‐apoptotic proteins (↓TNF‐α, ↓BAX, ↓Caspase‐3), and upregulates anti‐apoptotic Bcl‐2 expression.
Arman Norouzi‐Ghalehbala, Mohammadjavad Rezaei‐Varmaziar, Majid Taati, Ali Soleimanzadeh, Abbas Raisi, Farshid Davoodi, Amir Ali Shahbazfar   +6 more
wiley   +1 more source

Mechanistische Diversität in der photoangeregten Radikal‐Redoxchemie: Eine kritische Evaluierung

Angewandte Chemie, EarlyView.
Für viele prominente Beispiele der Photoredox‐Katalyse wird angenommen, dass sie über die Anregung einer offenschaligen („open‐shell“) Zwischenform des Katalysators ablaufen. Es wird jedoch intensiv darüber diskutiert, ob solche Mechanismen realistisch sind und, falls ja, wie genau sie ablaufen können.
Samuel J. Horsewill, Ryan Phelps, Joshua P. Barham, Daniel J. Scott   +3 more
wiley   +1 more source

NAD-dependent inhibition of the NAD-glycohydrolase activity in A549 cells.

, 2002
NAD glycohydrolases are enzymes that catalyze the hydrolysis of NAD to produce ADP-ribose and nicotinamide. Regulation of these enzymes has not been fully elucidated.
233:127 32, BALDUCCI, Enrico
core   +1 more source

Mechanistic Diversity in Photoexcited Radical Redox Chemistry: A Critical Evaluation

Angewandte Chemie International Edition, EarlyView.
Many high‐profile examples of photoredox catalysis are proposed to proceed via excitation of an open‐shell intermediate form of the catalyst. However, there is much debate over whether such mechanisms are realistic and, if so, exactly how they can occur.
Samuel J. Horsewill, Ryan Phelps, Joshua P. Barham, Daniel J. Scott   +3 more
wiley   +1 more source

Patient‐Reported Outcomes with Selpercatinib Among Patients with RET Fusion–Positive Non‐Small Cell Lung Cancer in the Phase I/II LIBRETTO‐001 Trial

The Oncologist, EarlyView., 2021
Abstract Background LIBRETTO‐001 is an ongoing, global, open‐label, phase I/II study of selpercatinib in patients with advanced or metastatic solid tumors. We report interim patient‐reported outcomes in patients with RET fusion–positive non‐small cell lung cancer (NSCLC).
Anna Minchom, Aaron C. Tan, Erminia Massarelli, Vivek Subbiah, Valentina Boni, Bruce Robinson, Lori J. Wirth, Lisa M. Hess, Min‐Hua Jen, Jennifer Kherani, Elizabeth Olek, Caroline E. McCoach   +11 more
wiley   +1 more source

Design and Optimization of a Double‐Column Vapor Recompression Heat Pump Distillation Process via NSGA‐II for Separating Ternary Wide‐Boiling Mixtures

Asia-Pacific Journal of Chemical Engineering, EarlyView.
ABSTRACT This study proposes a novel double‐column vapor recompression heat pump (DCVRHP) distillation process for separating ternary wide‐boiling‐range mixtures under two different vapor conditions: n‐hexane/n‐heptane/n‐octane using low pressure steam and n‐hexanol/n‐octanol/n‐decanol using high pressure steam.
Zeyang Li, Xiaoxin Gao, Xiaoyu Kang, Ruijie Wang, Xiyuan Chen   +4 more
wiley   +1 more source

The petrotympanic canal (Huguier canal): Evolutionary, anatomical, and medical perspectives

The Anatomical Record, EarlyView.
Abstract The petrotympanic canal, traditionally referred to as Civinini's or Huguier's canal, represents an anatomical passage connecting the middle ear and temporomandibular joint (TMJ). Despite its early description, its structural complexity and functional significance have often been underestimated. In this study, we combined historical, anatomical,
Andrea Papini, Nicola Montemurro, Ferdinando Paternostro, Immacolata Belviso, Massimo Galli, Petra Martini, Licia Uccelli, Jacopo Moggi‐Cecchi, Gregorio Oxilia   +8 more
wiley   +1 more source

Enhancing Meat Quality Through Dietary Fiber: Insights Into the Gut Microbiota‐Derived Short‐Chain Fatty Acids‐Muscle Axis

Animal Research and One Health, EarlyView.
Dietary fiber (DF) modulates meat quality through the gut‐muscle axis by reshaping gut microbiota, improving intestinal integrity, reducing inflammation, and regulating muscle metabolism. These mechanisms influence muscle fiber characteristics and post‐mortem biochemistry, thereby enhancing tenderness, juiciness, color, flavor, and nutritional value of
Zeshan Zulfiqar, Muhammad Arslan Asif, Layla Al‐Mitib, Nabeela Ashiq, Haojie Wang, Yalei Cui, Boshuai Liu, Shucheng Huang, Yinghua Shi   +8 more
wiley   +1 more source

Arthroscopic Suprapectoral Biceps Tenodesis Using a Standard Suture Anchor Is Safe and Effective

Arthroscopy, Sports Medicine, and Rehabilitation, EarlyView.
Purpose To evaluate the safety and efficacy of an arthroscopic technique of suprapectoral biceps tenodesis using a standard absorbable double‐loaded suture anchor. Methods This retrospective study includes all patients who underwent arthroscopic biceps tenodesis by the senior author between December 2017 and June 2020. Biceps tenodesis was performed in
Xavier A. Duralde, Caroline A. Heramb, Jennifer N. Blanda   +2 more
wiley   +1 more source

CASTOR1 regulates humoral immune responses and contributes to the pathogenesis of systemic lupus erythematosus

Arthritis &Rheumatology, Accepted Article.
Objectives CASTOR1 senses arginine and regulates mammalian target of rapamycin complex 1 (mTORC1), a central metabolic signaling molecule. This study aimed to elucidate the roles of CASTOR1 in humoral immune responses. Methods We analyzed human B cell transcriptomes from healthy controls and patients with systemic lupus erythematosus (SLE) via ...
Takeshi Kusuda, Toshihiko Komai, Takahiro Itamiya, Tatsuki Abe, Tomohisa Okamura, Keishi Fujio   +5 more
wiley   +1 more source