Results 31 to 40 of about 37,782 (205)

Compound heterozygous SLC12A5 variants expand the molecular and functional spectrum of KCC2‐developmental and epileptic encephalopathy

open access: yesEpilepsia, EarlyView.
Overview of the multimodal experimental approach integrating clinical, genetic, in silico, and in vitro investigations. Clinical: Representative EEG recording setup and ictal traces from affected patients. Genetic: Pedigrees for Families A and B highlighting the inheritance of the four identified SLC12A5 variants (A1, A2, B1, B2).
Mira Hamze   +19 more
wiley   +1 more source

Advanced ablation strategies for management of post-surgical atrial arrhythmias. [PDF]

open access: yes, 2013
Post-surgical arrhythmias include a wide range of arrhythmias occurring late after cardiac surgery and represent a complex substrate for catheter ablation either because of extended scar and remodeling or because of limited access to the area of interest.
Babu-Narayan, SV   +3 more
core   +1 more source

ENCEVIS: Evaluating the feasibility of an AI‐based algorithm as an assistant to neurophysiologists in clinical practice

open access: yesEpilepsia Open, EarlyView.
Abstract Objective This study evaluated the performance of the ENCEVIS artificial intelligence (AI)‐based algorithm as a screening tool to predict the presence of ictal and/or interictal epileptiform discharges (IEDs) in electroencephalography (EEG) recordings.
Aleksandre Tsereteli   +3 more
wiley   +1 more source

Exercising electrocardiograms from Thoroughbred racehorses with exercise associated sudden death

open access: yesEquine Veterinary Journal, EarlyView.
Abstract Background Exercise associated sudden death (EASD), defined as a fatal collapse in a closely monitored and previously presumed clinically healthy horse that occurs during exercise or within approximately 1 h after exercise, is disproportionately more common in equine than in human athletes.
Cristobal Navas de Solis   +3 more
wiley   +1 more source

Catheter Ablation: Evolution and Efficiencies

open access: yesJournal of Cardiovascular Electrophysiology, EarlyView.
ABSTRACT The present review includes a discussion the goals and pitfalls of efficiency in the medical profession, a historical perspective on the evolution of catheter ablation in the field of electrophysiology (EP), and the data regarding the relationship between efficiency and outcomes in the EP lab. Focus on efficacy is critical to maximize resource
Aravind G. Kalluri, Bradley P. Knight
wiley   +1 more source

Impact of Emergent Physician Notifications from Mobile Cardiac Outpatient Telemetry on Patient Outcomes (The EP‐COT Trial)

open access: yesJournal of Cardiovascular Electrophysiology, EarlyView.
ABSTRACT Introduction Mobile ambulatory cardiac telemetry (MCOT) use has increased over time; however, data on the prevalence and the impact of emergent arrhythmia notifications with MCOT remains unclear. We sought to determine the prevalence and clinical impact of emergent arrhythmia events in patients undergoing MCOT monitoring.
David Lin   +11 more
wiley   +1 more source

Atrial fibrillation and electrophysiology in transgenic mice with cardiac-restricted overexpression of FKBP12 [PDF]

open access: yes, 2019
Cardiomyocyte-restricted overexpression of FK506-binding protein 12 transgenic (αMyHC-FKBP12) mice develop spontaneous atrial fibrillation (AF). The aim of the present study is to explore the mechanisms underlying the occurrence of AF in αMyHC-FKBP12 ...
Ai, Tomohiko   +14 more
core   +1 more source

Prospective Trial of Radiofrequency Catheter Ablation of High Dominant Frequencies After Pulmonary Vein Isolation in Non‐Paroxysmal Atrial Fibrillation (PAD‐AF Trial): A Multicenter, Randomized Clinical Trial

open access: yesJournal of Cardiovascular Electrophysiology, EarlyView.
In persistent AF, adjunctive dominant frequency‐guided ablation after pulmonary vein isolation did not significantly improve outcomes. Limited overlap between high‐frequency sites and low‐voltage areas suggests functional–structural dissociation, while right atrial low‐voltage burden predicts recurrence.
Koji Kumagai   +10 more
wiley   +1 more source

Prevalence and Recovery of Arrhythmia‐Induced Cardiomyopathy in Patients With Newly Diagnosed Heart Failure Using a Wearable Defibrillator: A Real‐World Cohort Study

open access: yesJournal of Cardiovascular Electrophysiology, EarlyView.
This graphical abstract summarizes the study design and main findings in patients with newly diagnosed left ventricular systolic dysfunction and concomitant arrhythmia undergoing early rhythm control under wearable cardioverter‐defibrillator protection.
Joerg Yogarajah   +10 more
wiley   +1 more source

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