Results 71 to 80 of about 37,782 (205)

Force‐sensing catheters during pediatric radiofrequency ablation: The FEDERATION Study [PDF]

open access: yes, 2017
Background Based on data from studies of atrial fibrillation ablations, optimal parameters for the TactiCath (TC; St. Jude Medical, Inc) force‐sensing ablation catheter are a contact force of 20 g and a force‐time integral of 400 
Avari Silva, Jennifer N   +4 more
core   +2 more sources

Computational modelling of the pro‐ and antiarrhythmic effects of atrial high rate‐dependent trafficking of small‐conductance calcium‐activated potassium channels

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Small‐conductance calcium‐activated potassium (SK) channels are important for atrial repolarization and can be targeted for atrial‐specific antiarrhythmic treatments. We developed a computational model with a calcium sensor to study the effects of increased pacing rate (5 Hz), which enhances SK‐channel gating and forward ...
Stefan Meier   +3 more
wiley   +1 more source

Mechanisms of Supraventricular Tachycardia [PDF]

open access: yes, 1973
In summary, we have found a close association between the stress of A-V nodal conduction and the occurrence of atrial dispersion or aberration. We could not explain atrial dispersion on the basis of incomplete recovery of atrial activity, slowing of ...
Lazzara, Ralph, Scherlag, Benjamin J.
core   +1 more source

Atrial fibrosis in atrial fibrillation: Mechanisms, mapping techniques and clinical applications

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Summary of key aspects of atrial fibrosis in atrial fibrillation, highlighting atrial fibrosis as a hallmark of atrial fibrillation (AF). (1) Different types of fibrosis (blue), illustrating reparative and reactive fibrosis; (2) fibrosis detection techniques (green), illustrating late gadolinium enhancement cardiac magnetic ...
Caterina Vidal Horrach   +8 more
wiley   +1 more source

Frequency Analysis of Atrial Fibrillation From the Surface Electrocardiogram [PDF]

open access: yes, 2004
Atrial fibrillation (AF) is the most common arrhythmia encountered in clinical practice. Neither the natural history of AF nor its response to therapy are sufficiently predictable by clinical and echocardiographic parameters.
Bollmann, Andreas   +4 more
core  

Ganglionated plexi as neuromodulation targets for atrial fibrillation [PDF]

open access: yes, 2017
The autonomic nervous system plays an important role in the genesis of atrial fibrillation and is one of the candidate targets for atrial fibrillation therapy.
Chen, Peng-Sheng   +3 more
core   +1 more source

Deciphering pro‐arrhythmogenic mechanisms of EPAC in human atrial cardiomyocytes

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend This study aimed to investigate the effect of exchange proteins directly activated by cAMP (EPAC) on the regulation of human atrial cardiomyocyte electrophysiology and their potential involvement in the onset of atrial fibrillation (AF).
Arthur Boileve   +11 more
wiley   +1 more source

Skin sympathetic nerve activity precedes the onset and termination of paroxysmal atrial tachycardia and fibrillation [PDF]

open access: yes, 2017
Background Skin sympathetic nerve activity (SKNA) is useful for estimating sympathetic tone in humans. Objective The purpose of this study was to test the hypotheses that (1) increased SKNA is associated with the onset and termination of ...
Chen, Lan S.   +9 more
core   +1 more source

Small‐conductance Ca2⁺‐activated K⁺ channels in cardiac excitation–contraction coupling: Bridging mitochondria, sarcolemma and antiarrhythmic therapy

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Mitochondrial SK channel enhancement reduces cardiac arrhythmia trigger. Spontaneous sarcoplasmic reticulum (SR) Ca2+ release via hyperactive RyR2s underlies an increased arrhythmia trigger, promoting early and delayed afterdepolarizations during stress. Hyperactive RyR2s causes rise in cytosolic [Ca2+] during diastole. Clearance
Dmitry Terentyev   +7 more
wiley   +1 more source

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