Results 91 to 100 of about 226,833 (317)

Iron Deposition following Chronic Myocardial Infarction as a Substrate for Cardiac Electrical Anomalies: Initial Findings in a Canine Model [PDF]

open access: yes, 2013
Purpose: Iron deposition has been shown to occur following myocardial infarction (MI). We investigated whether such focal iron deposition within chronic MI lead to electrical anomalies. Methods: Two groups of dogs (ex-vivo (n = 12) and in-vivo (n = 10))
Cokic Ivan   +63 more
core   +1 more source

Exposure‐adjusted safety and efficacy of GLP‐I and GLP‐1/GIP receptor agonists compared with non‐GLP‐I for weight management and type 2 diabetes: Based on FDA medical and statistical reports of 34 280 safety and 36 312 efficacy subjects

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims This work aimed to contextualize glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) and glucose‐dependent insulinotropic polypeptide (GIP) receptor agonists safety and efficacy regarding weight management (WM); we analysed Food and Drug Administration (FDA) Medical Reviews to analyse 14 medications using patient‐exposure year normalization and ...
Aishwarya Prasad   +4 more
wiley   +1 more source

Acute toxicity of ADB‐CHMINACA ‐ a case series of patients with pronounced central nervous symptoms including the posterior reversible encephalopathic syndrome

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aim This report presents a series of 16 patients who were admitted to the emergency department following confirmed intake of the potent synthetic cannabinoid ADB‐CHMINACA. Methods The cases are drawn from a prospective observational study following the recreational use of synthetic cannabinoids.
Maren Hermanns‐Clausen   +7 more
wiley   +1 more source

Dexmedetomidine Versus Esmolol for Attenuation of Haemodynamic Response to Laryngoscopy and Tracheal Intubation in Hypertensive Patients

open access: yesInternational Journal of Anatomy Radiology and Surgery, 2018
Introduction: Direct laryngoscopy and endotracheal intubation is noxious stimulus associated with marked haemodynamic response, mediated by polysynaptic sympathetic pathway.
Kartik Sya   +3 more
doaj   +1 more source

Evaluating a virtual paediatric adverse drug reaction clinic

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims Adverse drug reactions (ADRs) are a common problem in paediatric health care. There is limited access to expertise in the evaluation and management of potential ADRs in children, limiting access to these services and creating delays in assessment and management.
Emily Hauck   +2 more
wiley   +1 more source

Arrhythmogenic Right Ventricular Cardiomyopathy: Prognostic Value of Electroanatomic Voltage Mapping [PDF]

open access: yes, 2013
Background: Endocardial voltage mapping (EVM) identifies low-voltage right ventricular (RV) areas, which may represent the electroanatomic scar substrate of life-threatening tachyarrhythmias.
MIGLIORE, FEDERICO
core  

Persistent Atrial Tachycardia Mimicking Inappropriate Sinus Tachycardia: A Case Report [PDF]

open access: yes, 2011
We report on a 57-year-old man with atrial tachycardia mimicking inappropriate sinus tachycardia that was sustained for 4 months despite pharmacotherapy.
Junichiro Koga, MD   +15 more
core   +1 more source

Identification of antibiotic allergies in children using prescribing patterns in the electronic medical record

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Background By age three, 5%–75% of children have a documented antibiotic allergy (AL). Despite this prevalence, recognition remains low because of limited clinician knowledge and time. Our study evaluates a novel approach to identifying AL using electronic medical record (EMR) prescription patterns.
Georgia Koutsaplis   +5 more
wiley   +1 more source

Do consumers and healthcare professionals report the same adverse event differently? A paired analysis of duplicate vaccine safety reports in Norway

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aim This study aimed to compare how Norwegian healthcare professionals (HCPs) and consumers reported the same adverse event (AE) following immunization with vaccines against COVID‐19 during the COVID‐19 pandemic. Specifically, we aimed to compare the extent to which HCPs and consumers reported information relevant for assessing the causal relationship ...
Tommy Emil Dzus   +4 more
wiley   +1 more source

Cardiotoxicity of new psychoactive substances – A review of experimental studies and real clinical and forensic cases

open access: yesAnnales Academiae Medicae Silesiensis
Designer drugs pose a serious modern health threat, specially the two most popular groups: synthetic cannabinoids and synthetic cathinones. Most of the available literature focuses on the neurological effects and scarcely describes effects on the ...
Rafał Skowronek, Alexander Suchodolski
doaj   +1 more source

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