Results 161 to 170 of about 275,633 (194)

Rare but relevant: Hydrocarbons and sudden sniffing syndrome

open access: yesAddiction, EarlyView.
Abstract Inhaled hydrocarbon‐associated sudden collapse (IHASC), often referred to as ‘sudden sniffing death syndrome’ is a critical and often fatal event linked to the inhalation of volatile hydrocarbons, primarily occurring in adolescents and young adults. This syndrome manifests as sudden cardiac and/or respiratory arrest, typically occurring during
Ingrid Berling   +1 more
wiley   +1 more source

Embedding Pharmacogenetics Into Clinical Practice to Improve Patient Outcomes

open access: yesAnnals of Human Genetics, EarlyView.
ABSTRACT Pharmacogenomics, the use of germline genomic data to guide prescription to improve effective and safer medication, holds promise as a clinical intervention. To date in most health systems, there has been limited uptake of pharmacogenomic testing confined to a few single drug–gene associations.
John Henry McDermott   +3 more
wiley   +1 more source

Systematic Review of Rare Major Adverse Cardiovascular Events Associated With the Treatment of Acne With Isotretinoin

open access: yesAustralasian Journal of Dermatology, Volume 66, Issue 3, Page e97-e108, May 2025.
ABSTRACT Acne vulgaris is a common inflammatory condition that is often treated by dermatologists with isotretinoin. Isotretinoin has a number of effects on inflammatory pathways, with clear efficacy in managing acne vulgaris. There are also well‐documented side effects of isotretinoin, including hyperlipidemia; however, the overall cardiovascular risk
Timothy L. Cowan   +3 more
wiley   +1 more source

Non‐Allergic Urticarial Skin Reactions Associated With MOv18 IgE, a First‐In‐Class IgE Antibody Recognising Folate Receptor Alpha

open access: yesAllergy, EarlyView.
MOv18 IgE, the first‐in‐class IgE antibody targeting the cancer antigen folate receptor alpha (FR⍺) showed early signs of efficacy and was well tolerated in a first‐in‐human clinical trial, with transient urticarial skin reactions as the most common toxicity.
Chara Stavraka   +28 more
wiley   +1 more source

Cardiovascular safety of testosterone therapy—Insights from the TRAVERSE trial and beyond: A position statement of the European Expert Panel for Testosterone Research

open access: yesAndrology, EarlyView.
Abstract Introduction Testosterone therapy has become a cornerstone treatment for men with hypogonadism, offering significant benefits such as improved sexual function, mood, muscle mass, and bone density. However, concerns about its cardiovascular safety have historically tempered its use.
Michael Zitzmann   +15 more
wiley   +1 more source

Clinical outcomes and feasibility of implementing outpatient labor induction with misoprostol: A prospective cohort study

open access: yesActa Obstetricia et Gynecologica Scandinavica, Volume 104, Issue 4, Page 647-657, April 2025.
In this prospective cohort study of 212 women undergoing Induction of Labour (IOL) with oral misoprostol, we found no significant differences in safety outcomes between outpatient and inpatient care. Our findings suggest that outpatient IOL with oral misoprostol may be a safe and feasible alternative, potentially reducing hospital stays, though larger ...
Kjersti Engen Marsdal   +6 more
wiley   +1 more source

Labor onset and delivery mode in women with congenital heart disease—A nationwide cohort study

open access: yesActa Obstetricia et Gynecologica Scandinavica, Volume 104, Issue 4, Page 666-675, April 2025.
In the growing population of women with congenital heart disease, most childbirths had spontaneous onset and were vaginal deliveries. Still, congenital heart disease in women was associated with a higher occurrence of induced labor and cesarean delivery compared to the reference population. Abstract Introduction More women with congenital heart disease
Marit Sandberg   +5 more
wiley   +1 more source

The Pivotal Role of an Early Post‐Acute Cardiac Rehabilitation as an Evidence‐Based Management of Left Ventricular Assist Device Patients

open access: yesArtificial Organs, Volume 49, Issue 5, Page 886-893, May 2025.
Early, intensive, post‐acute cardiac rehabilitation programs significantly improve functional capacity and disability in LVAD patients, similar to HFrEF patients admitted to the same program. Data support scientific recommendations suggesting implementation of early intensive cardiac rehabilitation in LVAD patients. ABSTRACT Background Left Ventricular
Massimo Pistono   +9 more
wiley   +1 more source

Influence of Preoperative Anatomical Characteristics on the Direction of Inflow Cannula in HeartMate 3

open access: yesArtificial Organs, EarlyView.
The IC direction in HM3 was influenced by the mitral valve height from the LV apex, distance between the LV apex and chest wall, and thoracic depth from the LV apex. Moreover, the IC direction in HM3 had little influence on the flow, PAWP and the survival rate of patients.
Shusuke Imaoka   +8 more
wiley   +1 more source

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