Results 311 to 320 of about 412,316 (368)

Light‐Activated Pharmacological Tools for Exploring the Cholinergic System

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT Cholinergic transmission plays a critical role in both the central and peripheral nervous systems, affecting processes such as learning, memory, and inflammation. Conventional cholinergic drugs generally suffer from poor selectivity and temporal precision, leading to undesired effects and limited therapeutic efficacy. Photopharmacology aims to
Alessio Colleoni   +5 more
wiley   +1 more source

Molecular Tools to Study and Control Dopaminergic Neurotransmission With Light

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT Dopaminergic neurotransmission is involved in several important brain functions, such as motor control, learning, reward‐motivated behavior, and emotions. Dysfunctions of dopaminergic system may lead to the development of various neurological and psychiatric disorders, like Parkinson's disease, schizophrenia, depression, and addictions ...
Galyna Maleeva   +5 more
wiley   +1 more source

Ivabradine for Incessant Atrial Tachycardia in a 1-Year-Old Child After Tetralogy of Fallot Repair. [PDF]

open access: yesCase Rep Cardiol
Balweel H   +5 more
europepmc   +1 more source

Akt Activation With IPL344 Treatment for Amyotrophic Lateral Sclerosis: First in Human, Open‐Label Study

open access: yesMuscle &Nerve, EarlyView.
ABSTRACT Introduction/Aims Akt intracellular signal transduction pathway dysfunction has been reported in people with amyotrophic lateral sclerosis (ALS) providing a novel target for intervention in this devastating progressive disease. This first‐in‐human study evaluated the safety, tolerability, and preliminary efficacy of the Akt pathway activator ...
Marc Gotkine   +9 more
wiley   +1 more source

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