Results 61 to 70 of about 1,904 (187)

A recombinant horseshoe crab plasma lectin recognizes specific pathogen-associated molecular patterns of bacteria through rhamnose. [PDF]

PLoS ONE, 2014
Horseshoe crab is an ancient marine arthropod that, in the absence of a vertebrate-like immune system, relies solely on innate immune responses by defense molecules found in hemolymph plasma and granular hemocytes for host defense.
Sim-Kun Ng, Yu-Tsyr Huang, Yuan-Chuan Lee, Ee-Ling Low, Cheng-Hsun Chiu, Shiu-Ling Chen, Liang-Chi Mao, Margaret Dah-Tsyr Chang   +7 more
doaj   +1 more source

A Comparative Study of Oncolytic Vaccinia Viruses Harboring Different Marine Lectins in Breast Cancer Cells

Marine Drugs, 2023
Our previous studies demonstrated that arming vaccinia viruses with marine lectins enhanced the antitumor efficacy in several cancer cells. This study aims to compare the efficacy of oncolytic vaccinia viruses harboring Tachypleus tridentatus lectin ...
Yanrong Zhou, Qianpeng Wang, Qi Ying, Xiaomei Zhang, Ting Ye, Kan Chen, Gongchu Li   +6 more
doaj   +1 more source

Bird's eye view of natural products for the development of new anti‐HIV agents: Understanding from a therapeutic viewpoint

Animal Models and Experimental Medicine, Volume 8, Issue 3, Page 441-457, March 2025.
Development of pharmaceutical drugs to cure HIV is crucial due to the current widespread epidemic. Nucleosides are the most effective anti‐HIV drugs, but their high toxicity and drug resistance limit their use. This review focuses on potential natural medicinal products for treating and managing HIV and AIDS.
Md. Al Amin, Mohamed H. Nafady, Mehrukh Zehravi, Sherouk Hussein Sweilam, Kusuma Praveen Kumar, M. Akiful Haque, Aziz Unnisa, Laliteshwar Pratap Singh, Mohammed Sayeed, Mohammed Ali Alshehri, Irfan Ahmad, Talha Bin Emran, Md. Zia Uddin   +12 more
wiley   +1 more source

Microbe-specific C3b deposition in the horseshoe crab complement system in a C2/factor B-dependent or -independent manner.

PLoS ONE, 2012
Complement C3 plays an essential role in the opsonization of pathogens in the mammalian complement system, whereas the molecular mechanism underlying C3 activation in invertebrates remains unknown.
Keisuke Tagawa, Toyoki Yoshihara, Toshio Shibata, Kazuki Kitazaki, Yuichi Endo, Teizo Fujita, Takumi Koshiba, Shun-ichiro Kawabata   +7 more
doaj   +1 more source

Identification, cellular localization, and function analysis of a novel toll‐like receptor (PtToll4) in Portunus trituberculatus

Journal of the World Aquaculture Society, Volume 56, Issue 1, February 2025.
Abstract Toll‐like receptor (TLR) is one of the most important pattern recognition receptors in both invertebrate and vertebrate animals. In previous study, three different kinds of TLR cDNAs (PtToll1‐3) have been cloned from Portunus trituberculatus. In this study, a novel PtToll4 cDNA sequence was identified in this crab. The PtToll4 ORF is predicted
Hao Liu, Feng‐Ling Shu, Dan‐Feng Zhang, Fei Yin, Su‐Ming Zhou   +4 more
wiley   +1 more source

Evolution and Viability of Asian Horseshoe Crabs Appear Tightly Linked to Geo‐Climatic Dynamics in the Sunda Shelf

Conservation Letters, Volume 18, Issue 1, January/February 2025.
ABSTRACT Horseshoe crabs are unique living fossils that have remained almost unaltered through 400 million years of global change. They face rapid worldwide declines under increasing anthropogenic pressure. Using comprehensive geographic and genomic sampling combined with approaches that integrate DNA with environmental and climatic datasets, we ...
Qian Tang, Akbar John, Yusli Wardiatno, Shin Nishida, Van Tu Do, Xiaoyong Xie, Siddhartha Pati, Handoko Adi Susanto, Sukree Hajisamae, Bryan Raveen Nelson, Wah Wah Min, Mohammad Eusuf Hasan, Tristan Salles, Yilin Chen, Yanhua Qu, Fumin Lei, Byrappa Venkatesh, Frank E. Rheindt   +17 more
wiley   +1 more source

The moulting arthropod: a complete genetic toolkit review

Biological Reviews, Volume 99, Issue 6, Page 2338-2375, December 2024.
ABSTRACT Exoskeletons are a defining character of all arthropods that provide physical support for their segmented bodies and appendages as well as protection from the environment and predation. This ubiquitous yet evolutionarily variable feature has been instrumental in facilitating the adoption of a variety of lifestyles and the exploitation of ...
Giulia Campli, Olga Volovych, Kenneth Kim, Werner P. Veldsman, Harriet B. Drage, Idan Sheizaf, Sinéad Lynch, Ariel D. Chipman, Allison C. Daley, Marc Robinson‐Rechavi, Robert M. Waterhouse   +10 more
wiley   +1 more source

Microsatellite and mitochondrial DNA analysis of the genetic structure of Chinese horseshoe crab (Tachypleus tridentatus) in southeast China coast

, 2016
Chinese horseshoe crab (Tachypleus tridentatus) is a Xiphosura animal of significant commercial importance and in danger of extinction in China. To better estimate how genetic structure can be used to obtain a conservation perspective of the species ...
Weng, Zhao Hong, Xie, Yang Jie, Wang, Zhi Yong, Xiao, Zhi Qun, Gui, Jian Fang   +4 more
core   +1 more source

Internal transcribed spacer as effective molecular marker for the detection of natural hybridization between the bivalves Pinna nobilis and Pinna rudis

Ecology and Evolution, Volume 14, Issue 8, August 2024.
The Pinna nobilis, a Mediterranean mollusc, has suffered population declines due to a mortality event linked to the parasite Haplosporidium pinnae, though some populations show resilience. This study developed a molecular multiplex‐PCR method using species‐specific primers to accurately identify P. nobilis, P. rudis, and their hybrids.
Gaetano Catanese, Maite Vázquez‐Luis, Salvatore Giacobbe, José Rafael García‐March, Maria Zotou, Prado Patricia, Orestis Papadakis, José Tena‐Medialdea, Stelios Katsanevakis, Amalia Grau   +9 more
wiley   +1 more source

Study on comparison of hemocytes from Apozomus zhensis (Arachnida) and Tachypleus tridentatus (Merostomata)(浙阿盾蝎与中国鲎血细胞的比较研究)

Zhejiang Daxue xuebao. Lixue ban, 2000
应用显微镜或相差显微镜对浙阿盾蝎(Apozomus zhensis)(蛛形纲：裂盾目)和中国鲎(Tachypleus tridentatus)(肢口纲)进行血细胞类型研究.浙阿盾蝎有原血细胞、浆细胞、颗粒细胞和类绛色细胞4种类型血细胞.并总结了节肢动物门螯肢动物亚门中两个主要类群的血细胞基本类型，其中肢口纲(鲎)的血细胞类型数目最少，蛛形纲的裂盾目(浙阿盾蝎)血细胞类型数目也较少.
CHENZhang-fu(陈樟福), LIYa-nan(李亚南), ZHANGZhen-hua(张贞华)   +2 more
doaj   +1 more source