Results 61 to 70 of about 5,112,054 (267)

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

Tacitní znalosti jako most mezi teorií a praxí v pedagogické přípravě budoucích učitelů. Tacit knowledge as a bridge between theory and practice in the domain-general aspect of teacher education. [PDF]

Pedagogická Orientace, 2012
The paper deals with tacit knowledge in the pedagogical component ofteacher education. Tacit knowledge is seen – metaphorically – as a bridge between theory and practice. In the paper, the concept of tacit knowledge is characterised; it is a concept that
Švec Vlastimil
doaj  

Establishing Tacit Knowledge Capture System in Project-Oriented Organizations Based on TOGAF Enterprise Architecture: A Systematic Review [PDF]

کتابداری و اطلاع‌رسانی
Objective: This study seeks to investigate how to establish a tacit knowledge capture system in project-oriented organizations based on TOGAF enterprise architecture. Methodology: Due to few research studies on how to implement enterprise architecture in
Mandana Hayati, Saeideh Ebrahimi, Alireza Nikseresht, Mahmood Javan, Zouhayr Hayati   +4 more
doaj   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

Molecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian, Sriraam Sivachandran, Melissa Galati, Brandon Ramchatesingh, Hibo Rijal, Johnny Hanna, Elena Netchiporouk, May Chergui, Margaret Redpath, Samy Abou Setah, Ivan V. Litvinov   +10 more
wiley   +1 more source

Extended Rationale-Based Model for Tacit Knowledge Elicitation in Requirements Elicitation Context

IEEE Access, 2020
The Requirements elicitation involves knowledge intensive and collaborative activities. Requirements engineering research has proposed a range of knowledge elicitation and requirements gathering techniques, few of which apply specific strategies for ...
Halah Abdulaziz Al-Alshaikh, Abdulrahman A. Mirza, Hessah Abdullah Alsalamah   +2 more
doaj   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

Organizational conditions associated with the sharing of tacit and explicit knowledge in the financial sector in Colombia

Knowledge Management & E-Learning: An International Journal
Knowledge sharing is the social interaction through which individuals exchange their tacit and explicit knowledge with others. Tacit knowledge comes from experience, talent, and reflection and is difficult to formalize, transfer, and communicate to ...
Delio Ignacio Castaneda, Camilo Andrés Ramírez Rojas   +1 more
doaj   +1 more source

Exploring tacit knowledge transfer and innovation capabilities within the buyer–supplier collaboration: a literature review

Cogent Business & Management, 2019
The study seeks to identify the main facilitators and barriers of tacit knowledge transfer that influence innovation capabilities of the supplier within the buyer–supplier collaboration.The conceptual paper is based on a systematic literature review of ...
S. Sikombe, M. Phiri
semanticscholar   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source