Results 131 to 140 of about 3,248 (232)

Prevalence and distribution of G6PD deficiency: implication for the use of primaquine in malaria treatment in Ethiopia. [PDF]

, 2019
BackgroundG6PD enzyme deficiency is a common enzymatic X-linked disorder. Deficiency of the G6PD enzyme can cause free radical-mediated oxidative damage to red blood cells, leading to premature haemolysis.
Koepfli, Cristian, Lee, Ming-Chieh, Lo, Eugenia, Pestana, Kareen, Raya, Beka, Yan, Guiyun, Yewhalaw, Delenasaw, Zhong, Daibin   +7 more
core  

Tafenoquine for the radical cure and prevention of malaria: the importance of testing for G6 PD deficiency [PDF]

, 2020
Robert J. Commons, James McCarthy, Ric N. Price   +2 more
openalex   +1 more source

Modulation of Antimalarial Activity at a Putative Bisquinoline Receptor in vivo Using Fluorinated Bisquinolines [PDF]

Antimalarials can interact with heme covalently, by - interactions or hydrogen bonding. Consequently, the prototropy of 4-aminoquinolines and quinoline methanols was investigated using quantum mechanics.
Alizadeh, S, Bisby, R, Cantú Reinhard, FG, Dascombe, MJ, de Visser, SP, Del Casino, A, Dempster, NM, Drew, MGB, Dunn, JF, Evans, PG, Fielding, AJ, Ismail, FMD, Nahar, L, Randle, LE, Sarker, SD   +14 more
core   +1 more source

Decision letter: Response to comment on 'The clinical pharmacology of tafenoquine in the radical cure of Plasmodium vivax malaria: An individual patient data meta-analysis'

, 2023

openalex   +1 more source

Relative efficacy of anti-Plasmodium vivax malaria combination drugs in preventing transmission to two major Anopheles mosquitoes in the first few days of treatment

International Journal of Infectious Diseases
Objectives: The World Health Organization recommends three drug anti-malarial combinations: cloroquine+primaquine, artesiminin+primaquine, and cloroquine+tafenoquine.
Erika Gómez Martinez, Rodrigo Maciel Alencar, Rosa Amélia Gonçalves Santana, Laila Rowena Albuquerque Barbosa, Anne Cristine Gomes de Almeida, Victor Irungu Mwangi, Sarah Regiane do Nascimento Rocha, Layne Even Borges de Souza, Lucyane Mendes Silva, Yudi Tatiana Pinilla, Norbert Becker, Wuelton Marcelo Monteiro, Marcus Vinicius Guimarães de Lacerda, Tainá Silva Secundino, Raquel Soares Maia Godoy, Nilton Barnabé Rodrigues, Nágila Francinete Costa Secundino, Gisely Cardoso de Melo, Paulo Filemon Paolucci Pimenta   +18 more
doaj   +1 more source

Plasmodium falciparum susceptibility to standard and potential anti-malarial drugs in Dakar, Senegal, during the 2013–2014 malaria season

, 2015
International audienceBackground: In 2006, the Senegalese National Malaria Control Programme recommended artemisinin-based combination therapy (ACT) as the first-line treatment for uncomplicated malaria.
Camara, Cheikhou, Diatta, Bakary, Diemé, Yaya, Dionne, Pierre, Fall, Bécaye, Fall, Mansour, Nakoulima, Aminata, Pradines, Bruno, Wade, Boubacar   +8 more
core   +3 more sources

A comprehensive revision on the use of quinoline antimalarial drugs as leishmanicidal agents

Frontiers in Chemistry
Antimalarial drugs based on quinolines have been widely used as leishmanicidal agents for either cutaneous or visceral leishmaniasis models. Herein, we showed the leishmanicidal response against in vitro models of different Leishmania spp. and against in
Romina E. Avanzo, Guadalupe García Liñares, Noris Rodríguez, Angel H. Romero   +3 more
doaj   +1 more source

A Randomized, Double‐Blind, Placebo‐Controlled, Dose‐Ranging Trial of Tafenoquine for Weekly Prophylaxis againstPlasmodium falciparum [PDF]

, 2003
Braden Hale, Seth Owusu‐Agyei, David J. Fryauff, Kwadwo Koram, Martin Adjuik, Abraham Oduro, William R. Prescott, J. Kevin Baird, Francis Nkrumah, Thomas L. Ritchie, Eileen D. Franke, Fred Binka, John Horton, Stephen L. Hoffman   +13 more
openalex   +1 more source

Glucose-6-phosphate dehydrogenase deficiency among malaria suspects attending Gambella hospital, southwest Ethiopia [PDF]

, 2014

core   +1 more source

Tafenoquine for children: a step towards implementation

The Lancet Child & Adolescent Health, 2022
Commons, RJ, Price, RN
openaire   +3 more sources