Results 281 to 290 of about 708,068 (294)

TRPM8 levels determine tumor vulnerability to channel agonists

Molecular Oncology, EarlyView.
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo, Francesco Giuseppe Carbone, Kristi Buzo, Nicole Annesi, Sacha Genovesi, Annalisa Lorenzato, Karen Widmann, Michela Libergoli, Elisa Marmocchi, Giovanni Bertalot, Alberto Brolese, Mauro Giulio Papotti, Luca Molinaro, Orazio Caffo, Mattia Barbareschi, Alberto Bardelli, Alessandro Romanel, Sabrina Arena, Andrea Lunardi   +18 more
wiley   +1 more source

Prediction of visceral pleural invasion of clinical stage IA lung adenocarcinoma based on computed tomography features. [PDF]

Transl Cancer Res
Lyu D, Wang Y, Tu W, Hu S, Ma Y, Zhou X, Xiao Y, Dong R, Fan L, Liu S.   +9 more
europepmc   +1 more source

Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer

Molecular Oncology, EarlyView.
Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte, Osheen Sharma, Laura Leuenberger, Emelie Wallin, Josefin Fernebro, Päivi Östling, Rebecka Bergström, Johan Lindberg, Ulrika Joneborg, Olli Kallioniemi, Brinton Seashore‐Ludlow   +10 more
wiley   +1 more source

Enhancing counterfeit RFID tag classification through distance based cognitive risk control. [PDF]

Sci Rep
Wu H, Wang S, Pu C, Ma J, Zeng Y.
europepmc   +1 more source

Epitope tags are not created equal: Disruption of cellular function of a translation factor by a short viral tag. [PDF]

MicroPubl Biol
Barker B, Cannon C, Umphlett H, Kim ES, Keiper BD.   +4 more
europepmc   +1 more source

Ecological drivers of movement for two sympatric marine predators in the California current large marine ecosystem. [PDF]

Mov Ecol
Irvine LM, Lagerquist BA, Schorr GS, Falcone EA, Mate BR, Palacios DM.   +5 more
europepmc   +1 more source

Powdery mildew induces chloroplast storage lipid formation at the expense of host thylakoids to promote spore production. [PDF]

Plant Cell
Xue H, Jaenisch J, Sasse J, McGarrigle ER, Choi EH, Louie K, Gutbrod K, Dörmann P, Northen TR, Wildermuth MC.   +9 more
europepmc   +1 more source

Migration to breeding areas by male sperm whales Physeter macrocephalus from the Northeast Atlantic Arctic. [PDF]

Sci Rep
Lydersen C, Blanchet MA, Kovacs KM, Similä T, Freitas C, Morange Z, Pedersen OM, Vogel EF, Bril M, Christensen G, Rikardsen AH.   +10 more
europepmc   +1 more source