Results 61 to 70 of about 12,778 (231)

Development of an experiment-based robust design paradigm for multiple quality characteristics using physical programming

, 2007
The well-known quality improvement methodology, robust design, is a powerful and cost-effective technique for building quality into the design of products and processes.
Antony, Jiju, Cho, Byung Rae, Kovach, Jami   +2 more
core   +1 more source

A Model Based Systems Engineering Framework for Digital Twins in Medical Device Innovation

Systems Engineering, EarlyView.
ABSTRACT Medical device development remains constrained by development processes centered largely in the physical domain. These methods limited early understanding of system behavior and prolonged timelines relative to other innovation pathways. Such limitations increase prototype cycle duration and the number of iterations required to resolve design ...
Tanguy René Pinol, Leon Hugh Prentice, Kate Fox, Toh Yen Pang   +3 more
wiley   +1 more source

Optimization of Parameters for Electrospinning of Polyacrylonitrile Nanofibers by the Taguchi Method

International Polymer Processing, 2017
Abstract This study empirically examined the influences of electrospinning process factors (applied voltage, feed rate of the polymer solution and tip-to-collector distance) and the polymer solution concentration on the diameters of electrospun polyacrylonitrile (PAN) nanofibers.
Celep, G. K., Dincer, K.
openaire   +1 more source

The Big Data Science Center at the Shanghai Synchrotron Radiation Facility: the architecture of the superfacility

Journal of Synchrotron Radiation, EarlyView.
The Big Data Science Center at the Shanghai Synchrotron Radiation Facility has developed a user‐friendly centralized superfacility platform that integrates the entire large scientific facility lifecycle into a single accessible solution for users, while ensuring that the data lifecycle remains compliant with the findability, accessibility ...
Xiaoyun Li, Chunpeng Wang, Jige Chen, Rongzheng Wan, Jing Ye, Qintong Li, Haojun Cai, Ying Zhang, Aiguo Li, Renzhong Tai, Alessandro Sepe   +10 more
wiley   +1 more source

Therapeutic targeting of bleomycin‐induced pulmonary fibrosis by human bone marrow mesenchymal stem cell‐derived extracellular vesicles and/or pirfenidone: Impact of sex in mature adult mice

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Idiopathic pulmonary fibrosis (IPF) is a progressive lung disease with limited therapeutic options. This study compared the therapeutic effects of bone marrow mesenchymal stem cell‐derived extracellular vesicles (BM‐MSC‐EVs) with an IPF treatment, pirfenidone (PFD), in mature adult mice with established pulmonary ...
Jennie S. Charoenphannathon, Simon G. Royce, Yasmin Higham, Jane E. Bourke, Chrishan S. Samuel   +4 more
wiley   +1 more source

Bridging Kidney Organoid Innovation and Regenerative Medicine: Current Advances and Future Directions

Cell Proliferation, EarlyView.
This review outlines kidney organoid differentiation strategies, key developmental mechanisms, and engineering and multi‐omics approaches driving their progress toward regenerative medicine. ABSTRACT Chronic kidney disease (CKD) has emerged as a critical public health challenge worldwide, and organ donor shortages underscore the urgent need for ...
Bohong Guo, Jingyuan Zhang, Xuening Fang, Yangyang Liu, Yueyang Deng, Yuxin Xue, Zhengxi Wang, Xiaotao Dong, Mengqi Jia, Xiaodong Li   +9 more
wiley   +1 more source

Optimization of Friction Stir Welding Parameters of AA5052-H32 Aluminium Alloy using Taguchi and Taguchi-Pareto Methods

, 2023
It is difficult to improve the quality of friction stir welded joints of AA5052-H32 material because of scarce metrics on its concurrent optimization and prioritization.
Rajan, John, Sawyerr, Babatunde Alade, Bamidele, Adetayo Moses, Oke, Sunday Ayoola, Adedeji, Kasali Aderinmoye, Fasina, Ebun, Oyetunji, Elkanah Olaosebikan   +6 more
core   +1 more source

A Sustainable Approach to Tensile Property Enhancement in Sand Casting Via Metal Chip–Sand Composite Molds

Journal of Materials Exploration and Findings
The present work focuses on the study of the effect of adding different weight percentages and particle sizes of various metal chips to foundry sand on the tensile strength of aluminum alloy castings, utilizing Taguchi's optimization methodology and ...
Maaruf Isyaku, Danjuma Saleh Yawas, Mathew Olatunde Afolayan, Terva Ause   +3 more
doaj   +1 more source

Suppression of Indoleamine 2,3‐Dioxygenase Enhances Immune Responses to the Therapeutic Vaccine for Chronic Hepatitis B

Hepatology Research, EarlyView.
Indoleamine 2,3‐dioxygenase (IDO) activity modulates immune responses to the therapeutic HBV vaccine NASVAC. Genetic or pharmacological suppression of IDO enhanced vaccine efficacy in mice, and lower serum kynurenine levels predicted favorable responses in humans, suggesting IDO as both a therapeutic target and a biomarker.
Yohei Shirakami, Soranobu Ninomiya, Takayasu Ideta, Ayumu Kanbe, Toshihide Maeda, Daisuke Minowa, Daisuke Taguchi, Masaya Kubota, Hiroyasu Sakai, Kenji Imai, Yasuko Yamamoto, Hiroyasu Ito, Kuniaki Saito, Osamu Yoshida, Yoichi Hiasa, Masahito Shimizu   +15 more
wiley   +1 more source

Application of Taguchi Method in the Optimization of Swimming Capability for Robotic Fish

, 2016
In this paper, we applied the Taguchi method to evaluate the maximum swimming speed of a robotic fish under the limitation of the output of the motor. Four factors were considered in the optimization: the caudal-fin aspect ratio, the caudal fin stiffness,
Lv J, Li, L (reprint author), Peking Univ, Coll Engn, Intelligent Control Lab, Beijing 100871, Peoples R China., Xie GM, 张星, Chen W, Wang W, Li L   +6 more
core   +1 more source