After HLA‐B*15:02 screening, the residual risk of carbamazepine‐induced nonimmediate cutaneous adverse reactions is 0.059. Among these HLA‐B*15:02‐negative cases, HLA‐B*15:11 and HLA‐B*15:21 carrier status significantly increases the risk of carbamazepine‐induced nonimmediate cADR.
Warit Ruanglertboon +11 more
wiley +1 more source
Performance of Tai Chi Chuan and NF-κB-driven proinflammatory gene expression (IL-6, IL-1β, TNF-α) in adult chronic disease patients: a systematic review and meta-analysis of randomized controlled trials. [PDF]
Zhu SQ, Wang H.
europepmc +1 more source
Regulatory harmonization: Evolution, globalization and future directions
Regulatory harmonization has become an increasingly important and accepted approach to streamline regulatory review processes and expedite access to safe, effective and high‐quality medicines globally. This review explores the evolution and current status of regulatory harmonization, convergence and reliance initiatives.
Orin Chisholm +2 more
wiley +1 more source
Characterizing virtual community exercise programs for people with mobility limitations: a scoping review. [PDF]
Barbosa Dos Santos R +6 more
europepmc +1 more source
Pharmacometric evaluation of pre‐referral rectal artesunate in children with severe malaria
Aims Parenteral artesunate is the preferred first‐line treatment for severe malaria. Pre‐referral rectal artesunate suppositories are recommended where parenteral treatment is inaccessible. In this study, we compared dihydroartemisinin exposure and model‐predicted early parasite clearance following rectal artesunate and intravenous artesunate in ...
Ayorinde Adehin +6 more
wiley +1 more source
Alterations of Cortical Thickness in High Suicidality Patients with Panic Disorder and Their Relationship with Symptomatology and Treatment Response. [PDF]
Ham JY +5 more
europepmc +1 more source
Introduction Warfarin therapy is the mainstay of anticoagulation treatment in South Africa and requires frequent INR monitoring due to interindividual patient variability. Time in therapeutic range (TTR) reflects the proportion of total treatment time during which INR values are within therapeutic range.
Masudah Paleker +3 more
wiley +1 more source
Sacred space in motion: geography, time, and texts in the historiography of Lingyan Temple. [PDF]
Han B, Liu Y.
europepmc +1 more source
Abstract Cooperative learning is a widely adopted teaching method to improve academic achievement. This review synthesises existing research on the use of cooperative learning within a school setting for pupils aged 11–16 years. Such a review has not been undertaken to date and will present an evidence base for educators considering implementation ...
Patricia Hampson +2 more
wiley +1 more source
The effect of Tai Chi on glycemic control in type 2 diabetes mellitus: a meta-analysis of randomized controlled trials. [PDF]
Sun Y, Li Q, Xue W.
europepmc +1 more source

