Results 51 to 60 of about 154,829 (285)

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

open access: yesMolecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed   +10 more
wiley   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

open access: yesFEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid   +3 more
wiley   +1 more source

The Changing Nature of Sino-Foreign Business Relationships, 1842-1941 [PDF]

open access: yes, 2000
During the second half of the nineteenth century, foreign business enterprises relied considerably upon the service of compradors to extend their economic interests in the Chinese economy.
Chan, Kai Yiu, Cox, Howard
core   +2 more sources

Immune‐Driven Expression in Inclusion Body Myositis With T‐Cell Large Granular Lymphocytic Leukemia

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives T‐cell large granular lymphocytic leukemia (T‐LGLL), reported in up to 58% of inclusion body myositis (IBM) patients, is a rare leukemia of cytotoxic or less commonly helper T cells. The range of myopathies in T‐LGLL and the impact of coexisting T‐LGLL in IBM are not well understood. Our objectives are to investigate the spectrum of
Pannathat Soontrapa   +10 more
wiley   +1 more source

Knizhnik-Zamolodchikov-type equations for gauged WZNW models

open access: yes, 1997
We study correlation functions of coset constructions by utilizing the method of gauge dressing. As an example we apply this method to the minimal models and to the Witten 2D black hole.
ALEX LEWIS   +6 more
core   +1 more source

Kai kurie teisės marksistinės teorijos klausimai

open access: yesProblemos, 2014
Straipsnyje nagrinėjama K. Marxo teisės teorijos svarbiausios sąvokos. Teigiama, kad atskleisdama teisės ryšį su ekonomine visuomenės struktūra, arba su tam tikra gamybinių jėgų išsivystymo pakopa, marksistinė teorija peržengė teisės ribas.
Vladas Rybakovas
doaj   +1 more source

Air Pollution and the Risk and Progression of Multiple Sclerosis: A Systematic Review and Meta‐Analysis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Purpose Air pollution has been linked to several neurological conditions, including stroke and neurodegenerative diseases. Evidence regarding its association with multiple sclerosis (MS) remains conflicting, limited by small sample sizes. Methods PubMed, Embase, Scopus, and Cochrane controlled register of trials (CENTRAL) were searched on ...
Ahmad A. Toubasi, Thuraya N. Al‐Sayegh
wiley   +1 more source

Kita proto pusė

open access: yesSociologija: Mintis ir Veiksmas, 1998
Racionalumo diskurso recepcija ir kritika yra sietina su Descartes'o filosofija. Būtent Descartes'as savo "Metafiziniuose apmąstymuose" suformuluoja pamatinius racionalumo filosofijos principus: abejonę, kaip mąstymo metodą; racionalaus ir sau tapataus ...
Audronė Žukauskaitė
doaj   +1 more source

Risk of Retinopathy Associated with Long‐Term Use of Hydroxychloroquine in Patients with Rheumatic Diseases: A Systematic Review and Meta‐Analysis

open access: yesArthritis Care &Research, Accepted Article.
Objective We aimed to estimate the prevalence and cumulative incidence of hydroxychloroquine retinopathy (HCQ‐R) and its risk factors among long‐term HCQ users with rheumatic diseases through a systematic review and meta‐analysis of observational studies that used spectral‐domain OCT (SD‐OCT) for screening. Methods A systematic search of PubMed, Scopus,
Narsis Daftarian   +4 more
wiley   +1 more source

Práctica de Tai Chi en ancianos, alternativa para mejorar su longevidad Practice of Tai Chi in the elderly, an alternative to better longevity

open access: yesRevista de Ciencias Médicas de Pinar del Río, 2012
El Tai Chi Chuan es un arte marcial efectivo como ejercicio para prolongar la vida. Con el objetivo de demostrar la eficacia de la práctica del Tai Chi en los ancianos para mejorar la longevidad, se realizó una investigación de intervención-acción ...
Odalys Roque Álvarez   +3 more
doaj  

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