Results 1 to 10 of about 129 (127)

Recognition of the 300-kDa Mannose 6-Phosphate Receptor Cytoplasmic Domain by 47-kDa Tail-Interacting Protein [PDF]

Proceedings of the National Academy of Sciences of the United States of America, 2000
Tail-interacting 47-kDa protein (TIP47) binds the cytoplasmic domains of the cation-dependent (CD) and cation-independent (CI) mannose 6-phosphate receptors (MPRs) and is required for their transport from endosomes to the Golgi complex. TIP47 recognizes a phenylalanine-tryptophan signal in the CD-MPR.
Suzanne R Pfeffer
exaly   +3 more sources

PAT family proteins pervade lipid droplet cores

Journal of Lipid Research, 2005
The PAT family proteins, named after perilipin, adipophilin, and the tail-interacting protein of 47 kDa (TIP47), are implicated in intracellular lipid metabolism. They associate with lipid droplets, but how is completely unclear.
Horst Robenek, Mirko J. Robenek, David Troyer   +2 more
doaj   +3 more sources

Adoption of PERILIPIN as a unifying nomenclature for the mammalian PAT-family of intracellular lipid storage droplet proteins

Journal of Lipid Research, 2010
The PAT family of proteins has been identified in eukaryotic species as diverse as vertebrates, insects, and amebazoa. These proteins share a highly conserved sequence organization and avidity for the surfaces of intracellular, neutral lipid storage ...
Alan R. Kimmel, Dawn L. Brasaemle, Monica McAndrews-Hill, Carole Sztalryd, Constantine Londos   +4 more
doaj   +1 more source

Decrease in intramuscular lipid droplets and translocation of HSL in response to muscle contraction and epinephrine

Journal of Lipid Research, 2006
A better understanding of skeletal muscle lipid metabolism is needed to identify the molecular mechanisms relating intramuscular triglyceride (IMTG) to muscle metabolism and insulin sensitivity.
Clara Prats, Morten Donsmark, Klaus Qvortrup, Constantine Londos, Carole Sztalryd, Cecilia Holm, Henrik Galbo, Thorkil Ploug   +7 more
doaj   +1 more source

Regulation of ADRP expression by long-chain polyunsaturated fatty acids in BeWo cells, a human placental choriocarcinoma cell line

Journal of Lipid Research, 2006
Transplacental transfer of maternal fatty acids is critical for fetal growth and development. In the placenta, a preferential uptake of fatty acids toward long-chain polyunsaturated fatty acids (LCPUFAs) has been demonstrated.
Kari Anne Risan Tobin, Nina Kittelsen Harsem, Knut Tomas Dalen, Anne Cathrine Staff, Hilde Irene Nebb, Asim K. Duttaroy   +5 more
doaj   +1 more source

PPARα activators and fasting induce the expression of adipose differentiation-related protein in liver

Journal of Lipid Research, 2006
The adipose differentiation-related protein (ADFP)/adipophilin belongs to a family of PAT (for perilipin, ADFP, and TIP47) proteins that associate on the surface of lipid droplets (LDs). Except for LD association, a clear role for ADFP has not been found.
Knut Tomas Dalen, Stine M. Ulven, Borghild M. Arntsen, Karianne Solaas, Hilde I. Nebb   +4 more
doaj   +1 more source

COPI complex is a regulator of lipid homeostasis.

PLoS Biology, 2008
Lipid droplets are ubiquitous triglyceride and sterol ester storage organelles required for energy storage homeostasis and biosynthesis. Although little is known about lipid droplet formation and regulation, it is clear that members of the PAT (perilipin,
Mathias Beller, Carole Sztalryd, Noel Southall, Ming Bell, Herbert Jäckle, Douglas S Auld, Brian Oliver   +6 more
doaj   +1 more source

A dynamic, cytoplasmic triacylglycerol pool in enterocytes revealed by ex vivo and in vivo coherent anti-Stokes Raman scattering imaging[S]

Journal of Lipid Research, 2009
The absorptive cells of the small intestine, enterocytes, are not generally thought of as a cell type that stores triacylglycerols (TGs) in cytoplasmic lipid droplets (LDs).
Jiabin Zhu, Bonggi Lee, Kimberly K. Buhman, Ji-Xin Cheng   +3 more
doaj   +1 more source

Adipocyte differentiation-related protein reduces the lipid droplet association of adipose triglyceride lipase and slows triacylglycerol turnovers⃞

Journal of Lipid Research, 2007
Although neutral lipid storage droplets are ubiquitous in eukaryotic cells, very little is known about how their synthesis and turnover are controlled. Adipocyte differentiation-related protein (ADRP; also known as adipophilin) is found on the surface of
Laura L. Listenberger, Anne G. Ostermeyer-Fay, Elysa B. Goldberg, William J. Brown, Deborah A. Brown   +4 more
doaj   +1 more source

Cloning, chromosome mapping and expression pattern of porcine PLIN and M6PRBP1 genes

Genetics Selection Evolution, 2008
The PAT proteins, named after the three PLIN/ADRP/TIP47 (PAT) proteins, PLIN for perilipin, ADRP for adipose differentiation-related protein and TIP47 for tail-interacting protein of 47 kDa, now officially named M6PRBP1 for mannose-6-phosphate receptor ...
Yang Zaiqing, Peichao Zhang, Xiaodong Chen, Yi Zhu, Bin Feng, Li Gan, Jihong Yuan, Tao Xia   +7 more
doaj   +1 more source