Results 211 to 220 of about 1,343,672 (294)

An epilepsy-associated KV3.1 potassium channel variant acts via dominant-positive effect. [PDF]

J Gen Physiol
Clatot J, Monnerie H, Panzer A, Platzer K, Goldberg EM.   +4 more
europepmc   +1 more source

The Comprehensive Live Cell‐Based Cytotoxicity Assay for Monitoring Disease Activity and Guiding Rescue Therapy in Acute Attacks of NMOSD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neuromyelitis optica spectrum disorder (NMOSD) is a devastating neurological disease that lacks serological biomarkers that can accurately reflect disease activity. We established a live cell‐based assay (LCBA) using serum with endogenous complement to quantify the overall cytotoxicity, offering a novel functional tool for monitoring
Xiaona Xu, Jie Ding, Yupeng Du, Guibao Luo, Jinming Li, Rui Liu, Xiaoyi Xu, Xiao Li, Minshu Li, Wei Jiang, Chunsheng Yang   +10 more
wiley   +1 more source

α-mannosidase I-dependent N-linked glycosylation affects hERG channel functional availability during reactivation. [PDF]

J Physiol Sci
Wei M, Sun H, Yin Y, Liu Y, Wang P, Yoshimura K, Kume S, Kurokawa T, Ono K, Ding L, Zheng M.   +10 more
europepmc   +1 more source

Utility of the APE2 Score as a Diagnostic Tool for Autoimmune Encephalitis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To retrospectively evaluate the diagnostic performance of the Antibody Prevalence in Epilepsy and Encephalopathy (APE2) score relative to clinician‐adjudicated autoimmune encephalitis (AE) and the Graus criteria in a tertiary neuroimmunology referral cohort, including antibody‐negative AE.
Bijoya Basu, Sophia F. Damman, Samhitha M. Rai, Hesham Abboud   +3 more
wiley   +1 more source

Tail-dependence of masting synchrony results in continent-wide seed scarcity

Szymkowiak J, Foest J, Hacket-Pain A, Journé V, Ascoli D, Bogdziewicz M.   +5 more
europepmc   +1 more source

Near-atomistic simulations reveal the molecular principles that control chromatin structure and phase separation. [PDF]

Nat Commun
Russell K, Chen Y, Espinosa JR, Farré-Gil D, Zhou H, Maristany MJ, Perez-Lopez JI, Huertas J, Orozco M, Rosen MK, Collepardo-Guevara R.   +10 more
europepmc   +1 more source

Cerebrospinal Fluid Over Plasma Links Analytes to Cognitive Decline in Older Adults at Risk for Alzheimer's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To identify inflammatory analytes in cerebrospinal fluid (CSF) and plasma associated with cognitive decline in cognitively normal (CN) older adults at risk for Alzheimer's disease (AD). Methods In a longitudinal study of 118 CN older adults (65–80 years, 54% APOE ε4, 26% preclinical AD), 1331 CSF and 1501 plasma analytes were ...
Jagan A. Pillai, Audrey Zhu, Chunxuan Ma, Ming Wang, Yifan Yang, Lynn M. Bekris, Maria Khrestian, Frank P. DiFilippo, Mikhail Nasrallah, Aaron Burberry, James B. Leverenz, Yuan Hou, Feixiong Cheng, Stephen M. Rao   +13 more
wiley   +1 more source

Designing Elastic Softening Under Compression via Dipole-Dipole Interactions: The Case of Na₂TiSiO₅. [PDF]

Small
Zhang P, Muñoz A, Bura N, Botella P, Popescu C, Pellicer-Porres J, Dong X, Errandonea D.   +7 more
europepmc   +1 more source

Ofatumumab Therapy and Long‐Term Seizure Outcomes of Patients With Relapsing Anti‐NMDA Receptor Encephalitis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective There is a lack of studies on seizure outcomes associated with ofatumumab therapy in patients for relapsing anti‐N‐methyl‐D‐aspartate (NMDA) receptor encephalitis. We aimed to evaluate long‐term seizure outcomes of ofatumumab therapy for relapsing anti‐NMDA receptor encephalitis.
Jian Wang, Mengjiao Li, Ping Kong
wiley   +1 more source

Exploring the impacts of wildlife trade on zoonotic spillover and disease outbreaks: A multiple-perspective study. [PDF]

One Health
Wang K, Pagani-Núñez E, Wang Z, Ren J, Wei X, Chen Y, Li BV, Ling C, Xiao L.   +8 more
europepmc   +1 more source