Results 61 to 70 of about 454,765 (293)

Relation between higher order comoments and dependence structure of equity portfolio [PDF]

, 2017
We study a relation between higher order comoments and dependence structure of equity portfolio in the US and UK by relying on a simple portfolio approach where equity portfolios are sorted on the higher order comoments.
Cerrato, Mario, Crosby, John, Kim, Minjoo, Zhao, Yang   +3 more
core   +2 more sources

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Modelling Dependence within Joint Tail Regions

Journal of the Royal Statistical Society Series B: Statistical Methodology, 1997
Summary Standard approaches for modelling dependence within joint tail regions are based on extreme value methods which assume max-stability, a particular form of joint tail dependence. We develop joint tail models based on a broader class of dependence structure which provides a natural link between max-stable models and weaker forms of
Ledford, A. W., Tawn, J. A.
openaire   +2 more sources

The role of histone modifications in transcription regulation upon DNA damage

FEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Assessing Market Risk in BRICS and Oil Markets: An Application of Markov Switching and Vine Copula

International Journal of Financial Studies, 2021
This paper investigates the dynamic tail dependence risk between BRICS economies and the world energy market, in the context of the COVID-19 financial crisis of 2020, in order to determine optimal investment decisions based on risk metrics.
John Weirstrass Muteba Mwamba, Sutene Mwambetania Mwambi   +1 more
doaj   +1 more source

Integration of circadian and hypoxia signaling via non‐canonical heterodimerization

FEBS Letters, EarlyView.
CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley   +1 more source

Risk Spillo Risk Spillover from World Ener orld Energy Mark gy Markets to Pakistan Agricultur akistan Agricultural Commodity Markets. An application of Dependence switching Copula model

Business Review, 2023
Using a time-dependent copulas model, this study attempts to investigate the risk spillover from global energy markets to Pakistan’s agricultural commodities market.
Hira Saeed , Rukhsana Bibi , Muhammad Tahir   +2 more
doaj   +1 more source

Wave Propagation in Gravitational Systems: Late Time Behavior [PDF]

, 1995
It is well-known that the dominant late time behavior of waves propagating on a Schwarzschild spacetime is a power-law tail; tails for other spacetimes have also been studied.
B.S. DeWitt, C. Gundlach, C. Gundlach, C.M. Bender, C.T. Cunningham, E. S. C. Ching, E.S.C. Ching, E.S.C. Ching, H. Poincaré, I.S. Gradshteyn, K. Young, N. Andersson, P. T. Leung, P.M. Morse, P.T. Leung, P.T. Leung, R. Lang, R. Lang, R.G. Newton, R.G. Newton, R.H. Price, S. Chandrasekhar, W. Kundt, W. M. Suen   +23 more
core   +3 more sources

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Wave tails in time-dependent backgrounds [PDF]

Physical Review D, 2002
It is well-known that waves propagating under the influence of a scattering potential develop ``tails''. However, the study of late-time tails has so far been restricted to time-independent backgrounds. In this paper we explore the late-time evolution of spherical waves propagating under the influence of a {\it time-dependent} scattering potential.
openaire   +2 more sources