Results 51 to 60 of about 529,179 (290)
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Large deviations for renormalized self-intersection local times of stable processes
, 2005 We study large deviations for the renormalized self-intersection local time of d-dimensional stable processes of index \beta \in (2d/3,d]. We find a difference between the upper and lower tail.
Bass, Richard, Chen, Xia, Rosen, Jay
core +2 more sources
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
How extreme is extreme? An assessment of daily rainfall distribution tails [PDF]
Hydrology and Earth System Sciences, 2013 The upper part of a probability distribution, usually known as the tail, governs both the magnitude and the frequency of extreme events. The tail behaviour of all probability distributions may be, loosely speaking, categorized into two families: heavy ...
S. M. Papalexiou +2 more
doaj +1 more source
On the Efficient Simulation of the Left-Tail of the Sum of Correlated Log-normal Variates
, 2017 The sum of Log-normal variates is encountered in many challenging applications such as in performance analysis of wireless communication systems and in financial engineering.
Alouini, Mohamed-Slim +3 more
core +1 more source
Probing dark energy models with extreme pairwise velocities of galaxy clusters from the DEUS-FUR simulations [PDF]
, 2014 Observations of colliding galaxy clusters with high relative velocity probe the tail of the halo pairwise velocity distribution with the potential of providing a powerful test of cosmology.
Alimi, Jean-Michel +3 more
core +2 more sources
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Extended Reaction Rate Integral as Solutions of Some General Differential Equations
, 2010 Here an extended form of the reaction rate probability integral, in the case of nonresonant thermonuclear reactions with the depleted tail and the right tail cut off, is considered. The reaction rate integral then can be looked upon as the inverse of the
AM Mathai +7 more
core +1 more source
BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma
FEBS Open Bio, EarlyView.The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru +6 more
wiley +1 more source
Animals, 2023 As tails are often docked within the first days of life, studies investigating tail malformations and injuries in sheep do not exist thus far. To address this gap in the literature, this research aimed to analyse the occurrence of vertebral anomalies and
Hannah Hümmelchen +5 more
doaj +1 more source