Results 111 to 120 of about 510,642 (302)
ABSTRACT Objective The Gold Coast criteria permit diagnosis of amyotrophic lateral sclerosis (ALS) even without upper motor neuron (UMN) signs. However, whether ALS patients with UMN signs (ALSwUMN) and those without (ALSwoUMN) share similar characteristics and prognoses remains unclear.
Hee‐Jae Jung +7 more
wiley +1 more source
Predicting Tail-related Risk Measures: The Consequences of Using GARCH Filters for non-GARCH Data [PDF]
We investigate the consequences for value-at-risk and expected short-fall purposes of using a GARCH filter on various mis-specified processes.
Amine JALAL, Michael ROCKINGER
core
Clustering Algorithm Reveals Dopamine‐Motor Mismatch in Cognitively Preserved Parkinson's Disease
ABSTRACT Objective To explore the relationship between dopaminergic denervation and motor impairment in two de novo Parkinson's disease (PD) cohorts. Methods n = 249 PD patients from Parkinson's Progression Markers Initiative (PPMI) and n = 84 from an external clinical cohort.
Rachele Malito +14 more
wiley +1 more source
A Discrete CVaR Framework for Industrial Hedging Under Commodity, Freight, and FX Risks
Raw material price volatility, freight rates, and foreign exchange all pose significant uncertainty for lithium-ion battery manufacturers, jeopardising procurement planning and financial stability. In this paper, we formulate a discrete Conditional Value-
Yanduo Li, Ruiheng Li, Xiaohong Duan
doaj +1 more source
Extreme Value Theory for Tail-Related Risk Measures [PDF]
Many fields of modern science and engineering have to deal with events which are rare but have significant consequences. Extreme value theory is considered to provide the basis for the statistical modeling of such extremes. The potential of extreme value
Evis Këllezi, Manfred Gilli
core
Extremal dependence structures and bounds of Tail Value-at-Risk [PDF]
Session 2Organized by The University of Hong Kong & Society of Actuaries (SOA)In quantitative risk management, we often need to deal with risk aggregation with dependence uncertainty.
Cheung, KC
core
Fluid Biomarkers of Disease Burden and Cognitive Dysfunction in Progressive Supranuclear Palsy
ABSTRACT Objective Identifying objective biomarkers for progressive supranuclear palsy (PSP) is crucial to improving diagnosis and establishing clinical trial and treatment endpoints. This study evaluated fluid biomarkers in PSP versus controls and their associations with regional 18F‐PI‐2620 tau‐PET, clinical, and cognitive outcomes.
Roxane Dilcher +10 more
wiley +1 more source
Effective risk exposure descriptions can be made using continuous distributions. To illustrate the level of exposure to a certain danger, it is better to use a single number, or at the very least, a small set of numbers.
Vahid Ranjbar +3 more
doaj +1 more source
Serum Soluble Mediator Signatures of Lupus Nephritis: Histologic Features and Response to Treatment
Objective Lupus nephritis (LN) management remains challenging, and novel noninvasive biomarkers are needed. This study quantified serum soluble mediators in the Accelerating Medicines Partnership (AMP) LN cohort to identify biomarkers of histologic features and treatment response.
Andrea Fava +48 more
wiley +1 more source
An extended Rayleigh Weibull model with actuarial measures and applications
In this article, we discuss a new extension of the Rayleigh-Weibull model using the Marshall-Olkin family of distributions. The proposed model is called the Marshall-Olkin-Rayleigh-Weibull (MORW) model.
Mohammed Elgarhy +2 more
doaj +1 more source

