Results 41 to 50 of about 745 (157)

Pain and Pain Management in Austrian Nursing Home Residents' Daily Lives: A Qualitative Study Guided by an Integrated Quality of Life Model for Older Adults

Nursing &Health Sciences, Volume 28, Issue 2, June 2026.
ABSTRACT Pain affects various aspects of nursing home residents' lives and their quality of life. The Integrated Conceptual Model of Quality of Life for Older Adults provides a holistic framework to understand factors influencing quality of life. Especially in Austria, knowledge about pain and its management in nursing home residents' daily lives is ...
Eva Pichler, Doris Eglseer, Daniela Schoberer, Christa Lohrmann, Sandra Zwakhalen, Manuela Hoedl   +5 more
wiley   +1 more source

Overproduction of 42 Amino Acids Long Amyloid Beta Leads to Activation of Secretory Autophagy and Development of Drusen‐Like Structures Originating From Retinal Pigment Epithelium

The FASEB Journal, Volume 40, Issue 5, 15 March 2026.
The role of 42 amino acids long amyloid beta (Aβ) in the retinal pigment epithelium (RPE) was investigated using 5xFAD mice model overproducing Aβ. The RPE cells of 5xFAD mice showed increased oxidative stress, accumulation of autophagy‐destined proteins, increased expression of secretory autophagy markers, and increase in epithelial‐to‐mesenchymal ...
Johanna Ruuth, Toni Tamminen, Elisa Toropainen, Heikki Tanila, Juha M. T. Hyttinen, Tarja Malm, Kai Kaarniranta, Ali Koskela   +7 more
wiley   +1 more source

Study of Trabekular Anatomic Structures on Biawak Water Bone (Varanus Salvator)

, 2021
Asian water lizards (Varanus salvator) is one of the species that is widespread in the region of South Asia and Southeast Asia, one of which is in the territory of Indonesia.
Amalia Hasni, Haniaturizqia, Miftahul Anwar   +2 more
core  

BRD4/MAP2K7/PGF Signaling Axis Promotes Senescence and Extracellular Matrix Metabolism of Nucleus Pulposus Cells in Intervertebral Disk Degeneration

Aging Cell, Volume 24, Issue 6, June 2025.
This study identifies BRD4 as a key regulator in intervertebral disk degeneration (IDD), linking its upregulation to NP cell senescence and disrupted ECM metabolism through the BRD4/MAP2K7/PGF signaling cascade, offering a potential therapeutic target for IDD treatment.
Guangzhi Zhang, Lei Li, Zhili Yang, Zhenyu Cao, Xuchang Hu, Yonggang Wang, Xuewen Kang   +6 more
wiley   +1 more source

Musculoskeletal mimics of lumbosacral radiculopathy

Muscle &Nerve, Volume 71, Issue 5, Page 816-832, May 2025.
Abstract Electrodiagnostic evaluations are commonly requested for patients with suspected radiculopathy. Understanding lower extremity musculoskeletal conditions is essential for electrodiagnostic medicine specialists, as musculoskeletal disorders often mimic or coexist with radiculopathy.
Emma A. Bateman, Christian D. Fortin, Meiqi Guo   +2 more
wiley   +1 more source

Comparing the therapeutic effect of local corticosteroid injections and laser in treating coccyx pains (sacrum) [PDF]

, 2015
Coccydynia (pain in the coccyx or tailbone) is a fairly common pain in the bottom of backbone that spreads towards sacrum and lower legs. Supportive treatments, such as corticosteroids, use of muscle relaxants and correction of body position can help ...
Mahmoudi, M., Moghtadaei, M., Taghavi, R., Shahverdi, S., Yeganeh, A., Saidifard, M.   +5 more
core  

The Impact of a Novel Methodological Process for Needling Scars, Fascia, and Muscles in the Management of Myofascial Dysfunction and Chronic Pain in a Population Living With Social and Health Inequities: Quantitative Findings From a Longitudinal Observational Pilot Study

Pain Research and Management, Volume 2025, Issue 1, 2025.
Background: Nonpharmacological interventions are necessary tools for managing chronic pain to reduce dependence on prescribed analgesic medications. myoActivation® is an innovative systematic nonpharmacological assessment and needling process to help reduce chronic pain related to myofascial dysfunction (MFD).
Ly Nguyen, Barb L. Eddy, Nicholas West, Jeffrey N. Bone, Leanne M. Currie, Gillian Lauder, King Hei Stanley Lam   +6 more
wiley   +1 more source

The value of applying a melatonin antagonist (Luzindole) in improving the success rate of the bipedal rat scoliosis model

BMC Musculoskeletal Disorders, 2017
Background An ideal animal model has always been the key to research the pathogenesis and treatment of adolescent idiopathic scoliosis (AIS), while available methods have obvious disadvantages. The deficiency of melatonin has been proved relating to AIS.
Shuo Yang, Chaojun Zheng, Jianyuan Jiang, Feizhou Lu, Xinlei Xia, Wei Zhu, Xiang Jin, Xiaosheng Ma   +7 more
doaj   +1 more source

Care as tyranny: Miscellaneous observations

Anthropology and Humanism, Volume 49, Issue 2, Page 93-104, December 2024.
Abstract This article focuses on undesired care transgressions that violate the intimacy, autonomy, and humanity of patients, pregnant women, and older people. Undesired care that hurts patients is referred to as “violence,” “abuse,” and “dehumanization.” This can take different forms: physical, verbal, and emotional, as well as deliberate negligence ...
Sjaak van der Geest, Coleta Platenkamp
wiley   +1 more source

Adjectives with the Meanings ‘Long’ and ‘Short’ in Horizontal and Vertical Dimensions: a Case Study of the Buryat Language and Dictionaries

Монголоведение, 2019
The paper examines adjectives denoting horizontal and vertical size (‘long’ and ‘short’) in the Buryat language and Russian-Buryat dictionaries. The analysis shows that adjectives to define objects in horizontal orientation are fewer than those dealing
Babasan D. Tsyrenov, Anna T. Abayeva
doaj   +1 more source