Comparative Effectiveness and Safety of Inebilizumab Versus Rituximab in AQP4‐IgG‐Positive NMOSD
ABSTRACT Objective Rituximab (anti‐CD20, RTX) and inebilizumab (anti‐CD19, INE) represent B‐cell‐depleting therapies used for aquaporin‐4 antibody‐positive (AQP4‐IgG+) neuromyelitis optica spectrum disorder (NMOSD); however, direct comparative evidence remains limited.
Jie Lin +11 more
wiley +1 more source
Distribution, mobility and exposure risk of rare earth elements, uranium and thorium in soils impacted by illegal cassiterite-monazite mining in the southeastern Amazon, Brazil. [PDF]
Rodrigues AAP +6 more
europepmc +1 more source
This research proposed to answer the problems in this research. The main case in this research is â How the law adjustment of submarine utilizing as tailing waste disposal medium applying submarine tailing disposal system is.â From the main case, the ...
, Prof. Dr. Marsudi Triatmodjo, S.H., LL.M. +1 more
core
T1 Over Squared Proton Density Ratio to Characterize Multiple Sclerosis Lesions
ABSTRACT Objective Differentiating remyelinated from demyelinated lesions in MS remains challenging without histological confirmation. This study introduces the T1‐to‐PD2 ratio (TPR) imaging approach and evaluates its ability to characterize MS lesions alongside other quantitative MRI (qMRI) metrics. Methods Thirty individuals with MS (mean age: 47.5 ±
Sarah J. Wright +10 more
wiley +1 more source
Preliminary Study on In Situ Immobilization of Pb, Cd, and Zn in Flotation Tailings and Metallurgical Slags Using Phosphate, Cement, and Iron-Based Additives. [PDF]
Bajda T, Korczak J.
europepmc +1 more source
The Multiple Sclerosis Severity Allele rs10191329A and Cognitive Function: A UK Biobank Study
ABSTRACT The genome‐wide association study of Multiple Sclerosis severity linked the genetic variant rs10191329A to long‐term disability and implicated brain resilience as a determinant of outcome. We hypothesised that rs10191329A might influence cognition in other neurological diseases and healthy controls.
Ioanna Zimianiti +5 more
wiley +1 more source
Hydrogen Carrier Gas Method Translation in Comprehensive Two-Dimensional Gas Chromatography for Sustainable Nontargeted Analysis. [PDF]
Fisher KM +2 more
europepmc +1 more source
Digital Cognitive Testing in Mitochondrial Disease: Validity and Challenges for Clinical Trial Use
ABSTRACT Background Primary mitochondrial disease is a group of genetic disorders caused by pathogenic variants in nuclear or mitochondrial DNA, often resulting in progressive neurodegeneration and cognitive decline. Current management is primarily supportive, though recent research offers hope for disease‐modifying treatments in the future.
Oksana Pogoryelova +9 more
wiley +1 more source
A seasonally explicit counterfactual framework reveals incomplete turbidity recovery in a tropical river seven years after a major mine-tailings disaster. [PDF]
Leal JS, Souza NF.
europepmc +1 more source

