Results 31 to 40 of about 410,563 (250)
Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng +8 more
wiley +1 more source
Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells
DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park +8 more
wiley +1 more source
When did the ROC abandon “Retaking the Mainland”? The transformation of military strategy in Taiwan
The question of when the government of the Republic of China abandoned “Retaking the Mainland” has not been clearly answered in previous studies. In this article, I attempt to address this by reexamining the transformation of Taiwan’s military strategy ...
Takayuki Igarashi
doaj +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
How to promote bike tourism globally
Purpose – The main purpose of this study is to find ways on how to promote bike tourism globally, and use Taiwan as a model to explore this aspect. Design – The development of the study structure involved brainstorming and the assistance of an expert ...
Chun-An Chen, Hsien-Li Lee
doaj +1 more source
The quality of education in Indonesia is still far from being expected. It is different from Taiwan. The government and people realize that a strong commitment to build and develop a national education system is a key determinant of the success of the ...
Mochamad Yusuf Efendi +2 more
doaj +1 more source
Welcome to the final issue of Volume 20, one-fifth of a century of Laser Therapy! As this issue reaches you in hard copy form, the majority of readers will be in the middle of the holiday season, and either shivering or enjoying glorious sunshine, depending on your hemisphere. Wherever you are, on behalf of the entire Editorial team, may I wish you the
openaire +3 more sources
RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu +21 more
wiley +1 more source
Objective Ambulatory care–sensitive conditions (ACSCs) serve as indicators of access, quality, and performance of the health system. This study aimed to determine rheumatoid arthritis (RA)‐specific ACSCs for use in the evaluation of care system access and quality.
Kara Irwin +7 more
wiley +1 more source
Objective The aim of this study was to characterize the prevalence and correlates of dietary supplement use, identify commonly used supplements, and evaluate potential supplement–medication interactions among adults with systemic lupus erythematosus (SLE).
Sarah L. Patterson +7 more
wiley +1 more source

