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Takotsubo syndrome is a reversible acute heart failure frequently precipitated by an emotional or physical stress. The clinical presentation resembles acute coronary syndrome. Pathogenesis is complex and may involve brain-heart axis and neuro-hormonal stunning of the myocardium.
Sanjiv Gupta, Madan Mohan Gupta
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Takotsubo syndrome (TTS) is currently regarded as a special type of acute coronary syndrome. The syndrome can be trigerred by emotional stress factors and more often by some severe non-cardiac conditions. The long-term outcome of TTS patients is similar to those with myocardial infarction.
Karolína, Poledníková, Petr, Toušek
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Takotsubo syndrome: lonely hearts [PDF]
Although the nosology of takotsubo syndrome (TTS) has shifted from an acute coronary syndrome–like condition to a heart failure phenotype, its pathology and clinical course still present many unresolved issues. This gap in our knowledge has a significant impact on the various phases of clinical practice: from a challenging differential diagnosis to ...
Rosa G. M., Tini G., Porto I.
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Pathophysiology of Takotsubo Syndrome [PDF]
Originally described by Japanese authors in the 1990s, Takotsubo syndrome (TTS) generally presents as an acute myocardial infarction characterized by severe left ventricular dysfunction. TTS, however, differs from an acute coronary syndrome because patients have generally a normal coronary angiogram and left ventricular dysfunction, which extends ...
PELLICCIA, FRANCESCO +3 more
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The Immunology of Takotsubo Syndrome
Takotsubo syndrome (TTS) is a disorder characterized by transient cardiac dysfunction with ventricular regional wall motion abnormalities, primarily thought to be caused by the effects of a sudden catecholamine surge on the heart. Although the majority of patients exhibit prompt recovery of their cardiac dysfunction, TTS remains associated with ...
Kenji Rowel Q. Lim +5 more
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Takotsubo syndrome, also known as Takotsubo cardiomyopathy, stress-induced cardiomyopathy, transient apical ballooning and broken heart syndrome, is a disease characterized by transient regional left ventricular systolic dysfunction. It is usually determined by emotional or physical stress.
Luminița-Bianca GROSU +1 more
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Molecular Mechanisms of Takotsubo Syndrome
Takotsubo syndrome (TTS) is a severe but reversible acute heart failure syndrome that occurs following high catecholaminergic stress. TTS patients are similar to those with acute coronary syndrome, with chest pain, dyspnoea and ST segment changes on electrocardiogram, but are characterised by apical akinesia of the left ventricle, with basal ...
Couch, LS, Channon, K, Thum, T
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Abstract Takotsubo syndrome occurs in 1-2% of patients admitted in the emergency department with suspicion of ST-segment elevation myocardial infarction (STEMI), over 90% being postmenopause women. Psycho-emotional or physical stress is the main trigger that causes the release of catecholamines, with an important role in the ...
Gheorghe Andronic +4 more
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Atypical Takotsubo syndrome [PDF]
A 52-year-old woman without cardiovascular risk factors was admitted with oppressive chest pain following an emotionally stressed situation. The ECG showed an ST segment elevation in leads V2–V3 and biphasic T-wave in anteroseptal and lateral leads (DI, aVL, V1–V3) (figure 1A).
Andreia, Fernandes +3 more
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Pathogenesis of Takotsubo Syndrome
Takotsubo syndrome (TTS) is an enigmatic disease with a multifactorial and still unresolved pathogenesis. Postulated mechanisms include catecholamine excess, coronary artery spasm, and microvascular dysfunction, however catecholamines seem to play a central role in the pathophysiology of TTS.
Masarone D +14 more
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