Results 61 to 70 of about 2,637 (175)

A Machine Learning Model for Diagnosing Opportunistic Infections in HIV Patients: Broad Applicability Across Infection Types

Journal of Cellular and Molecular Medicine, Volume 29, Issue 6, March 2025.
ABSTRACT Opportunistic infections (OIs) are the leading cause of hospitalisation and mortality among Human Immunodeficiency Virus‐infected (HIV‐infected) patients. The diverse pathogen types and intricate clinical manifestations associated present a formidable challenge to the timely diagnosis of these infections.
Hao Chen, Fanxuan Chen, Yijun Wang, Enna Cai, Wangzheng Pan, Yichen Li, Zefei Mo, Hao Lou, Chufan Ren, Chenyue Dai, Xingbo Shan, Hui Ye, Zhenwei Xu, Pu Dong, Han Zhou, Shuya Xu, Tianye Zhu, Mingzhi Su, Xingguo Miao, Xiaoqu Hu, Liang Hong, Yi Wang, Feifei Su   +22 more
wiley   +1 more source

Disseminated Infections with Talaromyces marneffei in Non-AIDS Patients Given Monoclonal Antibodies against CD20 and Kinase Inhibitors

Emerging Infectious Diseases, 2015
Infections with the fungus Talaromyces (formerly Penicillium) marneffei are rare in patients who do not have AIDS. We report disseminated T. marneffei infection in 4 hematology patients without AIDS who received targeted therapy with monoclonal ...
Jasper F.W. Chan, Thomas S.Y. Chan, Harinder Gill, Frank Y.F. Lam, Nigel J. Trendell-Smith, Siddharth Sridhar, Herman Tse, Susanna K.P. Lau, Ivan F.N. Hung, Patrick C.Y. Woo, Kwok-Yung Yuen   +10 more
doaj   +1 more source

Assessing the potential risk of human pathogen resistance to medical antifungal treatments arising from agricultural use of fungicides with the same mode of action

Plant Pathology, Volume 74, Issue 2, Page 578-594, February 2025.
A mechanistic basis is described for assessment of resistance risk to medical antifungal treatments from agricultural use of fungicides of the same mode of action. Abstract A mechanistic basis is described for assessment of resistance risk to medical antifungal treatments from agricultural use of fungicides of the same mode of action.
Neil Paveley, Frank van den Bosch, Michael Grimmer   +2 more
wiley   +1 more source

Exosomes released from macrophages infected with Talaromyces marneffei activate the innate immune responses and decrease the replication

Immunity, Inflammation and Disease, 2023
Introduction Recent studies have demonstrated that exosomes play roles in pathogenesis and in the treatment of various diseases. We explored the influence of exosomes released from Talaromyces marneffei (T.
Guangquan Ji, Shan Feng, Hong Ren, Wenhao Chen, Renqiong Chen   +4 more
doaj   +1 more source

Comparison of film array pneumonia panel to routine diagnostic methods and its potential impact in an adult intensive care unit in Hong Kong and the potential role of emergency departments

Hong Kong Journal of Emergency Medicine, Volume 31, Issue 4, Page 159-164, August 2024.
Abstract Background Pneumonia is a leading diagnosis for patients requiring critical care. Prediction of the causal organisms has proved challenging, and antibiotic overuse is a burning issue. Objective This study aimed to compare the results of the BioFire FilmArray Pneumonia Panel (PN Panel) to standard diagnostic methods and evaluate its potential ...
Ping Wu, Kin Ho Steven Ling
wiley   +1 more source

Talaromyces marneffei and Burkholderia cepacia Co-Infection in a HIV-Uninfected Patient with Anti-Interferon-γ Autoantibodies

Infection and Drug Resistance, 2021
Wen Zeng,1,2 Ye Qiu,1,2 Mengxin Tang,1,2 Hui Zhang,2 Mianluan Pan,1 Shudan Tang,2 Jianquan Zhang1 1Department of Respiratory and Critical Medicine, The Eighth Affiliated Hospital, Sun Yat-Sen University, Shenzhen, Guangdong, 518000, People’s ...
Zeng W, Qiu Y, Tang M, Zhang H, Pan M, Tang S, Zhang J   +6 more
doaj  

Small Interfering RNA Mediated Messenger RNA Knockdown in the Amphibian Pathogen Batrachochytrium dendrobatidis

Journal of Basic Microbiology, Volume 64, Issue 8, August 2024.
ABSTRACT RNA interference (RNAi) has not been tested in the pandemic amphibian pathogen, Batrachochytrium dendrobatidis, but developing this technology could be useful to elucidate virulence mechanisms, identify therapeutic targets, and may present a novel antifungal treatment option for chytridiomycosis.
Rebecca J. Webb, Alexandra A. Roberts, Catherine Rush, Lee F. Skerratt, Mark L. Tizard, Lee Berger   +5 more
wiley   +1 more source

Taxonomy and evolution of Aspergillus, Penicillium and Talaromyces in the omics era – Past, present and future

Computational and Structural Biotechnology Journal, 2018
Aspergillus, Penicillium and Talaromyces are diverse, phenotypically polythetic genera encompassing species important to the environment, economy, biotechnology and medicine, causing significant social impacts.
Chi-Ching Tsang, James Y.M. Tang, Susanna K.P. Lau, Patrick C.Y. Woo   +3 more
doaj   +1 more source

Methylcitrate cycle gene MCD is essential for the virulence of Talaromyces marneffei

Medical Mycology, 2019
AbstractTalaromyces marneffei (T. marneffei), which used to be known as Penicillium marneffei, is the causative agent of the fatal systemic mycosis known as talaromycosis. For the purpose of understanding the role of methylcitrate cycle in the virulence of T.
Liyan Xi, Eleftherios Mylonakis, Xiqing Li, Sha Lu, Jieming Chu, Chunmei Chen, Zhiwen Chen, Xing Xiao, Liya He, Jiao Feng   +9 more
openaire   +2 more sources

A case of naganishial pleuritis in a kidney transplant recipient

Respirology Case Reports, Volume 12, Issue 2, February 2024.
Herein, we describe the unusual case of a kidney transplant patient who presented with left pleural effusion. The diagnosis of Naganishia‐related pleural effusion was ultimately confirmed through pleuroscopy with pleural nodule biopsy. Abstract The Naganishia species is a mycosis, previously classified as a non‐neoformans Cryptococcus species.
Tanapat Tassaneeyasin, Dararat Eksombatchai, Prawat Chantharit, Arunee Singhsnaeh, Viboon Boonsarngsuk   +4 more
wiley   +1 more source