Results 1 to 10 of about 67 (66)
Hematology, Transfusion and Cell Therapy, 2021 Introdução: Pacientes com doença falciforme (DF) e β-talassemia com clínica grave, apresentam necessidade de transfusão sanguínea recorrente, aumentando o risco de aloimunização. A aloimunização ocorre devido à exposição a antígenos não próprios, levando
R Widmer +9 more
doaj +1 more source
Cancer, Volume 129, Issue 1, Page 107-117, 1 January 2023., 2023 Abstract Background The correlation between thalassemia and malignancies other than hepatocellular carcinoma (HCC) and the possible relationship between other hemoglobinopathies and tumor risk have been poorly evaluated. Methods Eight Italian specialized centers evaluated the incidence of malignant neoplasms in hemoglobinopathies as well as their sites
Raffaella Origa +20 more
wiley +1 more source
Hematology, Transfusion and Cell Therapy, 2023 Objetivo: Demonstrar a relevância do diagnóstico molecular na identificação de heterozigoto composto para beta talassemias HBB:c.118C>T (CD39) e HBB:c.-138C>T (-88C>T) em recém-nascido da triagem neonatal.
VS Ramos +8 more
doaj +1 more source
Journal of Cellular and Molecular Medicine, Volume 26, Issue 9, Page 2520-2528, May 2022., 2022 Abstract Although numerous patient‐specific co‐factors have been shown to be associated with worse outcomes in COVID‐19, the prognostic value of thalassaemic syndromes in COVID‐19 patients remains poorly understood. We studied the outcomes of 137 COVID‐19 patients with a history of transfusion‐dependent thalassaemia (TDT) and transfusion independent ...
Ibrahim El‐Battrawy +49 more
wiley +1 more source
Jornal de Pediatria (Versão em Português), 2019 Objective: The purpose of this study was to illustrate the association between vascular endothelial growth factor level and pulmonary artery hypertension in children with β‐thalassemia major.
Usama M. Alkholy +5 more
doaj +3 more sources
Transfusion, Volume 61, Issue 6, Page 1729-1739, June 2021., 2021 Abstract Background The average hemoglobin content of red cell concentrates (RCC) varies depending on the method of preparation. Surprisingly less data are available concerning the clinical impact of those differences. Study Design and Methods The effects of two types of RCC (RCC‐A, RCC‐B) on transfusion regime were compared in a non‐blinded ...
Maria Rita Gamberini +15 more
wiley +1 more source
Selecting β‐thalassemia Patients for Gene Therapy: A Decision‐making Algorithm
HemaSphere, Volume 5, Issue 5, May 2021., 2021 This expert opinion originally developed by a panel of the Italian Society of Thalassemias and Hemoglobinopathies (SITE), reviewed and adopted by the European Hematology Association (EHA) through the EHA Scientific Working Group on Red Cells and Iron, has been developed as priority decision‐making algorithm on evidence and consensus with the aim to ...
Donatella Baronciani +13 more
wiley +1 more source
PROTOCOLOS CLÍNICOS EM BETA-TALASSEMIA
Hematology, Transfusion and Cell Therapy, 2023 Objetivos: Este trabalho tem como objetivo realizar um levantamento estatístico sobre os principais protocolos de pesquisa clínica, utilizando o banco de dados do Clinical Trials, envolvendo terapia gênica em pacientes com beta-talassemia.
LAB Faria, FM Lima, JVDS Bianchi
doaj +1 more source
MICRORNAS EM HEMOGLOBINOPATIAS: UMA REVISÃO
Hematology, Transfusion and Cell Therapy, 2023 Introdução: Os microRNAs (miRNAs) são pequenos RNAs não codificantes que atuam na expressão gênica interferindo na degradação do mRNA resultando em alterações nos processos pós-traducionais, sendo que vários miRNAs podem se ligar a um único gene ...
DD Silva +4 more
doaj +1 more source
, 2023 HemaSphere, Volume 7, Issue S1, Page 17-17, April 2023.
C.Z. Cristina Zuccato +9 more
wiley +1 more source