Results 41 to 50 of about 2,782 (143)

Determinação da sobrecarga de ferro na talassemia pela IRM hepática e ferritina [PDF]

, 2008
Accumulation of iron in thalassemia causes organ damage and reduces patient survival due to heart lesions in the second decade of life. Iron deposits are monitored by direct (biopsy) and indirect methods (ferritin) with sequential data being better than ...
ANGULO, Ivan L., BAFFA, Oswaldo, CARNEIRO, Antonio A., COVAS, Dimas T., ELIAS JUNIOR, Jorge, VILELA, Guilherme   +5 more
core   +2 more sources

Abstract Book for the 2nd Sickle Cell & Thalassaemia Virtual Conference

, 2022
HemaSphere, Volume 6, Issue S1, Page 1-43, January 2022.
wiley   +1 more source

S144 A MULTICENTRE, RANDOMIZED, NON‐INFERIORITY TRIAL COMPARING THE EFFICACY OF DEFERIPRONE VERSUS DEFERASIROX IN PEDIATRIC PATIENTS AFFECTED BY TRANSFUSION‐DEPENDENT HEMOGLOBINOPATHIES (DEEP‐2 TRIAL)

HemaSphere, Volume 3, Issue S1, Page 23-24, June 2019., 2019
Background: While the efficacy and safety of deferiprone (DFP) in adult patients with transfusion‐dependent hemoglobinopathies (TDH) has been extensively studied, data in children are sparse. Aims: We report results of DEferiprone Evaluation in Pediatrics‐2 (DEEP‐2), (EudraCT Number 2012‐000353‐31), a Phase III multicentre, randomized, open label study
A. Kattamis, M. Felisi, G. Reggiardo, A. El‐Beshlawy, M. Bejaoui, L. Sherief, S. Christou, C. Cosmi, O. Della Pasqua, G.C. Del Vecchio, A. Filosa, H. Hassab, M. Kreka, R. Origa, M.C. Putti, M. Spino, P. Telfer, B. Tempesta, Y.C. Tsang, A. Zaka, F. Tricta, D. Bonifazi, A. Ceci, A. Maggio   +23 more
wiley   +1 more source

EHA2021 Virtual Congress Abstract Book

, 2021
HemaSphere, Volume 5, Issue S2, June 2021.
wiley   +1 more source

PF502 A PROPOSAL OF AN ALGORITHM FOR THE DIAGNOSIS OF TYPE 1 GAUCHER DISEASE STARTING FROM HYPERFERRITINEMIA IN ADULTS

HemaSphere, Volume 3, Issue S1, Page 203-208, June 2019., 2019
Background: Type 1 Gaucher disease (GD) is a pleiotropic disease due to biallelic mutations in GBA gene, causing a reduction or absence of the activity of beta‐glucocerebrosidase and accumulation of glucocerebroside in macrophages of several organs, mainly in the spleen, liver and bone marrow.
G. Marchi, F. Busti, A. Lira Zidanes, A. Castagna, D. Girelli   +4 more
wiley   +1 more source

Le Basi biochimiche e molecolari delle talassemie e la diagnosi dell'Alfa-talassemia eterozigote [PDF]

, 1982
Recent aspects of molecular and biochemical basis of thalassemic syndromes are described together with laboratory methods suitable for diagnosis and screening of heterozygous α ...
Masala, Bruno Lucio
core  

PF735 ECONOMIC MODEL TO EVALUATE THE COST‐EFFECTIVENESS OF SECOND‐LINE NILOTINIB VERSUS DASATINIB FOR THE TREATMENT OF PHILADELPHIA CHROMOSOME‐POSITIVE CHRONIC MYELOID LEUKEMIA (CML‐CP) IN GERMANY

HemaSphere, Volume 3, Issue S1, Page 321-322, June 2019., 2019
Background: For CML‐CP patients who are intolerant or resistant to treatment with imatinib, nilotinib and dasatinib are both second‐generation tyrosine kinase inhibitors (TKIs) that are approved for use after imatinib. With recent label updates and guidelines that are expected to reflect those, there is interest in determining the cost‐effectiveness of
D. Tran, D. Grima, M. Feuerbach, K. Filioussi, R. Viana   +4 more
wiley   +1 more source

Clinical and laboratorial diversity in the bantu haplotype of sickle cell anemia [PDF]

, 2006
Several factors have been identified as possibly being responsible for the diversity of sickle cell anemia patients symptoms, including gender, age, haplotypes and hemoglobin F levels.
Cipolotti, Rosana, Costa, Paulo J. M. S., Figueiredo, Maria Stella, Vilela, Rosana Q. B.   +3 more
core   +3 more sources

Long‐term outcomes of avascular necrosis in sickle cell disease using joint‐specific patient‐reported outcome measures: Results from a multicentre study

British Journal of Haematology, Volume 206, Issue 1, Page 310-319, January 2025.
Summary Avascular necrosis (AVN) is a prevalent and progressive complication in young patients with sickle cell disease (SCD), but no study evaluated the long‐term subjective and objective outcome measures. Oxford hip score (OHS) and Oxford shoulder scores (OSS) are validated joint‐specific patient‐reported outcome measures (PROMs). In this prospective
Maddalena Casale, Giuseppe Toro, Federica Porcelli, Alessandra Quota, Rosamaria Rosso, Vincenzo Spadola, Francesco Arcioni, Saveria Campisi, Domenico Roberti, Silverio Perrotta   +9 more
wiley   +1 more source

ESTUDO FAMILIAL DE CASO DE HETEROZIGOSE COMPOSTA PARA HEMOGLOBINA KORLE-BU E BETA TALASSEMIA: RELATO DE CASO

Hematology, Transfusion and Cell Therapy
Objetivo: Relatar um estudo familial de probando com hemoglobina (Hb) Korle-Bu e β talassemia. Material e métodos: Amostras de sangue total do probando, sexo masculino, 8 meses e de seus progenitores (mãe com 31 anos e pai com 26 anos), provenientes do ...
GA Bernardino, EP Noronha, ACM Berti, VS Ramos, LA Souza-Junior, AVC Aguiar, E Belini-Junior   +6 more
doaj   +1 more source