Background: There are around 40,000 new cases of malignant pleural effusion in the UK each year. Insertion of talc slurry via a chest tube is the current standard treatment in the UK.
Rahul Bhatnagar +5 more
doaj +10 more sources
Talc slurry versus thoracoscopic talc insufflation for malignant pleural effusion: a systematic review and meta-analysis [PDF]
Objective: Talc pleurodesis is a widely used treatment option for malignant pleural effusion (MPE). However, the optimal form of administration remains controversial. Thus, we performed a systematic review and meta-analysis to assess the effectiveness of
Anna Luíza Soares de Oliveira Rodrigues +4 more
doaj +5 more sources
Intrapleural Fibrinolytic Therapy Improves Results With Talc Slurry Pleurodesis. [PDF]
Objective Talc slurry pleurodesis (TSP) can lead to permanent small loculations. Intrapleural tissue plasminogen activator (tPA) breaks down loculations, and therefore may improve results but may also inhibit pleurodesis.
Bellini A +4 more
europepmc +4 more sources
Malignant pleural effusions and the role of talc poudrage and talc slurry: a systematic review and meta-analysis [v2; ref status: indexed, http://f1000r.es/52v] [PDF]
Background: Malignant Pleural Effusion (MPE) is common with advanced malignancy. Palliative care with minimal adverse events is the cornerstone of management.
Srinivas Mummadi +2 more
doaj +3 more sources
Risk factors related to pleural empyema after talc slurry pleurodesis. [PDF]
Empyema is a complication of talc-pleurodesis that may lead to further surgical intervention and death. Therefore, the present study's objective was to identify the risk factors for the development of post-pleurodesis empyema after talc slurry pleurodesis in order to better select patients for this procedure and minimize its morbidity.Patients with ...
D'Ambrosio PD +5 more
europepmc +6 more sources
Predictors of talc slurry pleurodesis success in patients with malignant pleural effusions
Introduction: Malignant pleural effusions are an important burden of malignant disease. Slurry talc pleurodesis remains one of the most common and effective therapeutic options.
P.S. Santos +4 more
doaj +4 more sources
A Comparison of the Efficacies of OK-432 and Talc Slurry for Pleurodesis in Patients with Prolonged Air Leak after Pulmonary Resection. [PDF]
Purpose: A prolonged air leak (PAL) is one of the common postoperative complications of pulmonary resection. The aim of this study was to evaluate the efficacy and safety of pleurodesis with sterile talc or OK-432 for postoperative air leak.
Watanabe T +6 more
europepmc +2 more sources
Importance Malignant pleural effusion (MPE) is challenging to manage. Talc pleurodesis is a common and effective treatment. There are no reliable data, however, regarding the optimal method for talc delivery, leading to differences in practice and ...
Bhatnagar R +42 more
europepmc +2 more sources
Effectiveness and Safety of Talc Slurry Pleurodesis in the Treatment of Patients with Malignant Pleural Effusion and Low Karnofsky Performance Status Scores. [PDF]
Background/Objectives: Malignant pleural effusion is a common and distressing complication of advanced cancer, often resulting in severe symptoms such as dyspnoea, which significantly impacts patients’ quality of life.
Kastrati E +5 more
europepmc +2 more sources
OPTIMUM: a protocol for a multicentre randomised controlled trial comparing Out Patient Talc slurry via Indwelling pleural catheter for Malignant pleural effusion vs Usual inpatient Management. [PDF]
Introduction The development of malignant pleural effusion (MPE) results in disabling breathlessness, pain and reduced physical capability with treatment a palliative strategy.
Sivakumar P +6 more
europepmc +2 more sources

