Results 291 to 300 of about 1,492,877 (359)

Correction to "With and for the Patient: The Knowledges Embodied in Nurses' Practices-of-Work in Acute Care". [PDF]

Nurs Inq
europepmc   +1 more source

Defining the chromatin-associated protein landscapes on Trypanosoma brucei repetitive elements using synthetic TALE proteins

Carloni R, Devlin T, Tong P, Spanos C, Auchynnikava T, Rappsilber J, Matthews KR, Allshire RC.   +7 more
europepmc   +1 more source

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TALE: A tale of genome editing

Progress in Biophysics and Molecular Biology, 2014
Transcription activator-like effectors (TALEs), first identified in Xanthomonas bacteria, are naturally occurring or artificially designed proteins that modulate gene transcription. These proteins recognize and bind DNA sequences based on a variable numbers of tandem repeats.
Feng Wang, Yun Bai
exaly   +3 more sources

Engineering Broad-Spectrum Bacterial Blight Resistance by Simultaneously Disrupting Variable TALE-Binding Elements of Multiple Susceptibility Genes in Rice

Molecular Plant, 2019
Xanthomonas oryzae pv. oryzae (Xoo), the causal agent of bacterial blight of rice, recruits transcription activator-like effectors (TALEs) to induce expression of OsSWEET genes, which function in sugar transport and disease susceptibility (S).
Zhengyin Xu, Sai Wang, Bo Zhu
exaly   +2 more sources

A tale of two databases: the use of Web of Science and Scopus in academic papers

Scientometrics, 2020
Web of Science and Scopus are two world-leading and competing citation databases. By using the Science Citation Index Expanded and Social Sciences Citation Index, this paper conducts a comparative, dynamic, and empirical study focusing on the use of Web ...
Junwen Zhu, Weishu Liu
semanticscholar   +1 more source

The FusX TALE Base Editor (FusXTBE) for Rapid Mitochondrial DNA Programming of Human Cells In Vitro and Zebrafish Disease Models In Vivo

bioRxiv, 2021
Functional analyses of mitochondria have been hampered by few effective approaches to manipulate mitochondrial DNA (mtDNA) and a lack of existing animal models.
A. Sabharwal, B. Kar, Santiago Restrepo-Castillo, S. Holmberg, Neal D. Mathew, Benjamin L Kendall, Ryan P. Cotter, Zachary WareJoncas, Christoph Seiler, Eiko Nakamaru-Ogiso, K. Clark, S. Ekker   +11 more
semanticscholar   +1 more source

Cantilever Tales

Science, 2000
Building even the simplest nanomachines is a daunting challenge, but working models serve as springboards to grander designs. A classic example is the cantilever, an indispensable cog in the nanoworld that ushered in the scanning probe microscopy revolution. Today cantilevers, which resemble tiny diving boards, are the operating principle behind a host
openaire   +2 more sources

Riluzole and edaravone: A tale of two amyotrophic lateral sclerosis drugs

Medicinal research reviews (Print), 2018
Over the past decades, a multitude of experimental drugs have been shown to delay disease progression in preclinical animal models of amyotrophic lateral sclerosis (ALS) but failed to show efficacy in human clinical trials or are still waiting for ...
M. Jaiswal
semanticscholar   +1 more source