Results 31 to 40 of about 14,478 (262)

CDK4/MERCs/PINK1 Axis Drives PFOA/HFPO‐TA‐Induced Cardiac Senescence via Mitophagy Defect and cGAS‐STING Activation: In Vitro Amelioration by Cycloastragenol

Advanced Science, EarlyView.
The present study demonstrated that PFOA and HFPO‐TA exposure suppressed CDK4, disrupted MERCs and impaired PINK1/Parkin‐mediated mitophagy, thereby accelerating cardiac senescence, whereas CAG effectively reversed these pathological changes in vitro. Our findings identify CDK4 as a critical regulator bridging mitophagy defects and cardiac senescence ...
Nuo‐Wa Li, Jun‐Ze Jiang, Ying‐Ying Liu, Tian‐Tian Zhang, Kanwar Kumar Malhi, Xin Yao, Jin‐Long Li   +6 more
wiley   +1 more source

THE MAIN CAUSES OF UNSATISFACTORY OUTCOMES OF TREATMENT FOR FOOT INJURIES

Неотложная медицинская помощь, 2018
Background. The foot is a special anatomical structure in its complexity. A large number of articular and ligamentous structures provide effective amortization and adaptation to surface features when walking.
V. O. Kalensky, P. A. Ivanov
doaj   +1 more source

Pertumbuhan rumput laut lokal dan rumput laut hasil kultur jaringan Performance growth of local and tissue culture Seaweed Kappaphycus alvarezii

JFMR-Journal of Fisheries and Marine Research, 2020
Tujuan penelitian ini adalah untuk mengetahui perbedaan pertumbuhan rumput laut Kappaphycus alvarezi bibit lokal dan bibit hasil kultur jaringan. Penelitian dilakukan di perairan Seriweh Jerowaru Kabupaten Lombok Timur West Nusa Tenggara.
Nunik Cokrowati, Nanda Diniarti, Dewi Nur'aeni Setyowati, Alis Mukhlis   +3 more
doaj   +1 more source

Posterior ankle arthroscopic treatment of a talar chondroblastoma with allograft and a platelet-rich plasma-fibrin glue: A case report and literature review

Frontiers in Surgery, 2023
Talar chondroblastoma, which is a benign tumor of immature cartilage cells, is an uncommon but easily missed diagnosis of foot pain. Arthroscopic treatment for this condition is a safe, powerful, and promising technique with definitive advantages of ...
Cheng Chen, ZhenDong Li, JianFeng Xue, ZhongMin Shi   +3 more
doaj   +1 more source

Keeping Pace or Falling Behind? The Depth of Latin American Trade Agreements

Applied Economic Perspectives and Policy, EarlyView.
ABSTRACT This article examines whether Latin American countries are keeping pace with global trends in trade agreement depth or falling behind. Using 681 agreements (1970–2019), we develop the Depth Index of Trade Agreements (DITA) to weight provisions endogenously through factor analysis based on co‐occurrence patterns.
Raphael Gomes da Silva, Fernanda Aparecida Silva, Lia Nogueira   +2 more
wiley   +1 more source

Incomplete climate‐driven peripatric speciation in Moehringia sect. Moehringia (Caryophyllaceae) in the European Alps

American Journal of Botany, EarlyView.
Abstract Premise The origin of endemic species in the European Alps is commonly attributed to the climatic oscillations of the Quaternary. Moehringia sect. Moehringia, with 12 of 15 species endemic to the Alps and mostly restricted to well‐known glacial refugia, is a prime system for investigating the diversification of a lineage originating in the ...
Joachim W. Kadereit, Kirra McLeod, Audie M. Putra, Gudrun Kadereit, Diego F. Morales‐Briones   +4 more
wiley   +1 more source

The Culturally and Linguistically Diverse Workforce in Early Childhood Education: Findings From a National Survey of Australian Centre‐Based Services

Australian Journal of Social Issues, EarlyView.
ABSTRACT Culturally responsive early childhood education (ECE) environments can increase child and family participation, enhance service quality, and improve developmental outcomes for children. Educators from culturally and linguistically diverse (CALD) backgrounds contribute to inclusive ECE and are crucial for addressing workforce shortages.
Sene Gide, Linda Harrison, Sandie Wong, Frances Press, Belinda Davis   +4 more
wiley   +1 more source

Public Attitudes Toward Compassionate Release of Older People From Prison: Findings From a National Survey in Australia

Australian Journal of Social Issues, EarlyView.
ABSTRACT The rapid increase in older people in prison populations worldwide is generating significant health, cost, and human rights pressures on custodial systems. Compassionate release for older, frail inmates is a potentially effective response, yet little is known about public support for this approach.
Ye In (Jane) Hwang, Natasha Ginnivan, Amanuel Kidane Hagos, Tony Butler   +3 more
wiley   +1 more source

Becoming adults: exploring the late ontogeny of the human talus

Frontiers in Ecology and Evolution, 2023
IntroductionThe talus plays an important role in receiving and dissipating the forces and linking the leg and the foot. As such, it is of paramount importance to analyze how its morphology, internal and external, changes during late ontogeny and through ...
Carla Figus, Rita Sorrentino, Kristian J. Carlson, Kristian J. Carlson, Antony Colombo, Antony Colombo, Eugenio Bortolini, Federico Bernardini, Federico Bernardini, Igor Erjavec, Tamás Hajdu, Tamás Szeniczey, Orsolya Mateovics-László, Ildiko Pap, Claudio Tuniz, Mario Novak, Maria Giovanna Belcastro, Timothy M. Ryan, Stefano Benazzi   +18 more
doaj   +1 more source

Comparative cross-sectional study of optimal screw positioning in the talus during arthroscopic ankle arthrodesis: a computed tomography-based analysis of talar bone density

BMC Musculoskeletal Disorders
Background To achieve successful osteosynthesis during arthroscopic ankle arthrodesis, increased stability and compression pressure during fixation are needed.
Satoshi Kamijo, Tsukasa Kumai, Yasuhito Tanaka   +2 more
doaj   +1 more source