Results 1 to 10 of about 8,558 (112)

Metronomic chemotherapy in the neoadjuvant setting: results of two parallel feasibility trials (TraQme and TAME) in patients with HER2+ and HER2− locally advanced breast cancer [PDF]

Brazilian Journal of Medical and Biological Research, 2015
Neoadjuvant chemotherapy has practical and theoretical advantages over adjuvant chemotherapy strategy in breast cancer (BC) management. Moreover, metronomic delivery has a more favorable toxicity profile.
V. Petry, D.M. Gagliato, A.I.C. Leal, R.J. Arai, E. Longo, F. Andrade, M.D. Ricci, J.R. Piato, R. Barroso-Sousa, P.M. Hoff, M.S. Mano   +10 more
doaj   +3 more sources

Lipid-associated macrophages in the tumor-adipose microenvironment facilitate breast cancer progression

OncoImmunology, 2022
The tumor-adipose microenvironment (TAME) is a universal microecosystem, that is characterized by the dysfunction of lipid metabolism, such as excessive free fatty acids (FFAs).
Zhou Liu, Zhijie Gao, Bei Li, Juanjuan Li, Yangyang Ou, Xin Yu, Zun Zhang, Siqin Liu, Xiaoyu Fu, Hongzhong Jin, Juan Wu, Si Sun, Shengrong Sun, Qi Wu   +13 more
doaj   +1 more source

The expression profile of genes associated with behavior, stress, and adult neurogenesis along the hippocampal dorsoventral axis in tame and aggressive foxes

Вавиловский журнал генетики и селекции, 2023
The hippocampus plays the key role in stress response regulation, and stress response appears to be weakened in domesticated animals compared to their wild relatives.
Yu. V. Alexandrovich, E. V. Antonov, S. G. Shikhevich, A. V. Kharlamova, L. V. Meister, Y. V. Makovka, D. V. Shepeleva, R. G. Gulevich, Yu. E. Herbeck   +8 more
doaj   +1 more source

Tame Topology

Computer Sciences & Mathematics Forum, 2023
Alexander Grothendieck suggested creating a new branch of topology, called “topologie modérée”. In a paper by N. A’Campo, L. Ji, and A. Papadopoulos the authors conclude that no such tame topology has been developed at a purely topological level.
Artur Piękosz
doaj   +1 more source

TaME-seq2: tagmentation-assisted multiplex PCR enrichment sequencing for viral genomic profiling

Virology Journal, 2023
Background Previously developed TaME-seq method for deep sequencing of HPV, allowed simultaneous identification of the human papillomavirus (HPV) DNA consensus sequence, low-frequency variable sites, and chromosomal integration events.
Alexander Hesselberg Løvestad, Milan S. Stosic, Jean-Marc Costanzi, Irene Kraus Christiansen, Hege Vangstein Aamot, Ole Herman Ambur, Trine B. Rounge   +6 more
doaj   +1 more source

Genotyping-By-Sequencing (GBS) Detects Genetic Structure and Confirms Behavioral QTL in Tame and Aggressive Foxes (Vulpes vulpes). [PDF]

PLoS ONE, 2015
The silver fox (Vulpes vulpes) offers a novel model for studying the genetics of social behavior and animal domestication. Selection of foxes, separately, for tame and for aggressive behavior has yielded two strains with markedly different, genetically ...
Jennifer L Johnson, Helena Wittgenstein, Sharon E Mitchell, Katie E Hyma, Svetlana V Temnykh, Anastasiya V Kharlamova, Rimma G Gulevich, Anastasiya V Vladimirova, Hiu Wa Flora Fong, Gregory M Acland, Lyudmila N Trut, Anna V Kukekova   +11 more
doaj   +1 more source

Taming the landscape of effective theories

Journal of High Energy Physics, 2022
We introduce a generalized notion of finiteness that provides a structural principle for the set of effective theories that can be consistently coupled to quantum gravity.
Thomas W. Grimm
doaj   +1 more source

Effect of single ethanol administration on behavior and the consumption and preference of ethanol in tame and aggressive rats

Вавиловский журнал генетики и селекции, 2016
According to the hypothesis of stress relief, a high level of anxiety or stress may cause greater alcohol consumption and alcohol addiction. However, data obtained with experimental animals do not always confirm this statement.
R. V. Kozhemyakina, S. G. Shikhevich, A. Cagan, R. G. Gulevich   +3 more
doaj   +1 more source

مقایسه کینتیک آنزیم تریپسین تخلیص شده از ضمائم پیلوریک ماهی کیلکای معمولی (Clupeonella cultriventris caspia) با استفاده از سوبسترای سنتتیک آمیدی و استری [PDF]

مجله بهره‌برداری و پرورش آبزیان, 2015
در مطالعه حاضر پارامترهای کینتیک آنزیم تریپسین تخلیص شده از ضمائم پیلوریک ماهی کیلکای معمولی (C.cultriventris caspia) با استفاده از سوبسترای آمیدی (BAPNA) و استری (TAME) مورد بررسی قرار گرفت. نتایج حاصل از مقایسه کینتیک آنزیم تریپسین بین سوبسترای BAPNA و
عباس زمانی, رسول مدنی, مسعود رضائی   +2 more
doaj  

Seasonal Patterns in Growth Hormone, Insulin and Insulin-like Growth Factor-1 in Female Muskoxen

Rangifer, 1997
Over a year, mean serum growth hormone concentrations ranged from 0.5 to 3 ng/ml in tame muskoxen with the lowest values and fewest pulses between October and January. Serum insulin ranged from 0.25 to 0.92 ng/ml, with minima in summer. There were marked
Jan Z. Adamczewski, Susan C. Tedesco, Bernhard Laarveld, Peter F. Flood   +3 more
doaj   +1 more source