Results 171 to 180 of about 2,979,830 (287)

Boronic Acid Inhibitors of β‐Lactamases: A Promising Strategy Against Antimicrobial Resistance

Medicinal Research Reviews, EarlyView.
ABSTRACT The rise of antimicrobial resistance (AMR) poses a critical threat to global health, mostly due to the proliferation of β‐lactamases, a class of enzymes responsible for the inactivation of β‐lactam antibiotics. Among the most promising strategies to restore β‐lactam efficacy is the use of β‐lactamase inhibitors (BLIs), with boronic acid ...
Nicolò Santi, Federico Corsini, Robert A. Bonomo, Emilia Caselli, Fabio Prati   +4 more
wiley   +1 more source

Compliance by Design: Governing AI-Augmented Quantitative Analysis in Clinical and Translational Research. [PDF]

Clin Transl Sci
Zhang H, Khan S, Tan CY.
europepmc   +1 more source

Neurological Adverse Effects Associated With Commonly Used H1‐Antihistamines: A Narrative Review of Age‐Stratified Risk Profiles in Paediatric and Geriatric Populations

Medicine Advances, EarlyView.
This narrative review examines the neurological adverse effects associated with commonly used H1‐antihistamines, focusing on how blood–brain barrier (BBB) penetration and patient age influence central nervous system (CNS) toxicity. The major finding is that first‐generation antihistamines, because of higher CNS penetration, are associated with ...
Syeda Samia Fatima, Zahabia Adnan, Rabia Nizam, Marium Fawad, Zainab Mehmood, Areeba Asif, Ali Aamir   +6 more
wiley   +1 more source

An intelligent cloud firewall framework for multi-cloud security using lstm anomaly detection and federated learning. [PDF]

Sci Rep
V A, S KSR.
europepmc   +1 more source

Optimizing Ex Vivo MRI and Controlling the Roll of the Specimen Using Container‐ and Brain‐Specific 3D‐Printed Holders

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose Positioning and stabilizing a specimen in a container in preparation for ex vivo MRI are challenging. In addition, ex vivo MRI is often performed using preclinical scanners with gradient nonlinearity and nonhomogeneous sensitivity, requiring optimal placement.
Sethu K. Boopathy Jegathambal, Stefano Bambace, Sarah Kim, Junqi Wang, Angela Xiaomeng Zhu, Gurucharan Marthi Krishna Kumar, Ziqi Hao, Han Ru Liu, Aleksandra Bortel, Jérémie P. Fouquet, David A. Rudko, Amir Shmuel   +11 more
wiley   +1 more source

A multi-layer airport security framework using YOLO-based X-ray detection, video anomaly analysis, IoT sensor monitoring and blockchain logging. [PDF]

Sci Rep
Shobha T, Rashmi R, Chaitanya LR, Medhini CV, Chandana RJ, Gowda SP.   +5 more
europepmc   +1 more source

In Vivo Dynamic D2O‐MRI for Quantifying Apparent CSF Water Renewal Across Ventricular and Extraventricular Compartments

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose The choroid plexus has long been regarded as the principal source of cerebrospinal fluid (CSF), yet this view remains unresolved. We developed a dynamic indirect D2O MRI approach to quantify regional apparent CSF water renewal in vivo in rats at 9.4 T.
Zhao Zhang, Yun Wu, Yanmin Zheng, Zhuoyang Lin, Ye Li, Qiong Ye   +5 more
wiley   +1 more source

On Order Restricted Inference in Multi‐Step Stage Life Testing for a General Family of Distributions

Naval Research Logistics (NRL), EarlyView.
ABSTRACT Recently, k$$ k $$‐step stage life testing (SLT) has been proposed by Laumen and Cramer (2021) as a natural extension of progressive censoring with fixed censoring times (PC‐FCT) as well as of simple step‐stress accelerated life testing (SSALT).
Erhard Cramer, Ayan Pal, Debashis Samanta   +2 more
wiley   +1 more source

Blockchain and Internet of Medical Things for Resilient Healthcare. [PDF]

Bioengineering (Basel)
Di Grezia G, Clemente A, Dugheri S, Mattei V, Gili A, Mari E, Urraro F, Mucci N, Baldassarre A.   +8 more
europepmc   +1 more source

In Utero HSC Transplantation for Sickle Cell Disease: A Potential Therapeutic Approach That Overcomes Complications of Current Therapies

Prenatal Diagnosis, EarlyView.
ABSTRACT Sickle cell disease (SCD) affects millions worldwide but has limited treatment options, most of which carry significant side effects. At present, the only curative treatment for SCD is allogeneic or gene‐modified autologous hematopoietic stem cell (HSC) transplantation (Tx).
Oluwaseun O. Babatunde, Madeleine G. Bibby, Anthony Atala, Graça Almeida‐Porada, Christopher D. Porada   +4 more
wiley   +1 more source