Results 201 to 210 of about 348,025 (296)

Late steps of allelic break-induced replication suppress tandem duplication associated with BRCA1 deficiency. [PDF]

Nucleic Acids Res
Huang ZC, Feng YL, Liu Q, Chen RD, Liu SC, Wang M, Xie AY.   +6 more
europepmc   +1 more source

Genomic organization, intragenic tandem duplication, and expression analysis of chicken TGFBR2 gene. [PDF]

Poult Sci, 2022
Ning B, Huang J, Xu H, Lou Y, Wang W, Mu F, Yan X, Li H, Wang N.   +8 more
europepmc   +1 more source

ISAba1‐mediated crp‐osmC amplification enhances host‐associated fitness in Acinetobacter baumannii

mLife, EarlyView.
Abstract Acinetobacter baumannii is a pathogen, highly adaptable to both hospital‐ and host‐associated environments. Understanding the genetic mechanisms underlying its adaptability is critical for controlling its persistence. Our study identified the crp‐osmC gene cluster, flanked by ISAba1 elements, as a significant genetic structure undergoing ...
Da‐Wei Wei, Jiangqing Huang, Hailing Fang, Xinyu Wang, Gang Zhang, Chao Wang, Yuqin Song, Jie Feng   +7 more
wiley   +1 more source

Autosomal-dominant macular dystrophy linked to a chromosome 17 tandem duplication. [PDF]

JCI Insight
Adele R, Hussein R, Tavares E, Ahmed K, Di Scipio M, Charish J, Liang M, Monis S, Tumber A, Chen X, Paton TA, Roslin NM, Eileen C, Ivakine E, Sunny NE, Wilson MD, Campos E, Rajala RV, Maynes JT, Monnier PP, Paterson AD, Héon E, Vincent A.   +22 more
europepmc   +1 more source

Structural Variation Sequencing of 26 Amniotic Fluid Samples With Partial Gene Duplications and Postnatal Follow‐Up of the Fetuses

Prenatal Diagnosis, EarlyView.
ABSTRACT Objectives Partial gene duplications (PGDups) are a significant contributor to genetic disease. The precise genomic location and structure of PGDups are often unresolved using conventional methods, so prenatal diagnosis for PGDups is challenging, especially without ultrasound abnormalities.
Shengfang Qin, Xueyan Wang, Mengjia Yan, Yuxia He, Zhuo Zhang, Yan Yin, Jin Wang, Beibei Guo, Jing Wang, Na Xi, Zhaokai Li   +10 more
wiley   +1 more source

Optimizing treatment selection and timing of allogeneic haematopoietic stem cell transplantation in acute myeloid leukaemia with concurrent feline McDonough sarcoma (FMS)-like tyrosine kinase 3 internal tandem duplication, nucleophosmin 1 and deoxyribonucleic acid (DNA) methyltransferase 3 alpha mutations. [PDF]

Br J Haematol
Li R, Yao Y, Yang D, Mao L, Lou Y, He Y, Meng H, Yu W, Pang A, Feng S, Tong H, Han M, Jin J, Tang M, Jiang E, Wang H.   +15 more
europepmc   +1 more source

FLT3 Internal Tandem Duplication [PDF]

, 2020
openaire   +1 more source

Targeting ribonucleotide reductase to enhance the antileukemic activity of gilteritinib against chemoresistant <i>FLT3</i>- internal tandem duplication acute myeloid leukemia. [PDF]

ASPET Discov
Eid N, Zhao J, Thibodeau J, Edwards H, Li J, Bao X, Polin L, Kushner J, Dzinic SH, White K, Buck SA, Back JB, Stemmer PM, Lee M, Kim S, Taub JW, Ge Y.   +16 more
europepmc   +1 more source

A novel TRKB-activating internal tandem duplication characterizes a new mechanism of receptor tyrosine kinase activation. [PDF]

NPJ Precis Oncol
Brown LM, Tax G, Acera Mateos P, de Weck A, Foresto S, Robertson T, Jalud F, Ajuyah P, Barahona P, Mao J, Dolman MEM, Wong M, Mayoh C, Cowley MJ, Lau LMS, Sadras T, Ekert PG.   +16 more
europepmc   +1 more source

MLL Partial Tandem Duplication [PDF]

, 2020
openaire   +1 more source