Results 231 to 240 of about 348,025 (296)

Schisandrin C Targets PPARγ to Induce Ferroptosis in Colorectal Cancer Cells and Promote M1 Macrophage Polarization

Phytotherapy Research, EarlyView.
Schisandrin C: A Dual Anti‐Colorectal Cancer Strategy Targeting PPARγ. ABSTRACT Colorectal cancer (CRC) remains a leading cause of cancer mortality, necessitating novel therapeutic strategies. Schisandrin C (SinC), a bioactive lignan from Schisandra chinensis, exhibits diverse pharmacological activities, but its anti‐CRC mechanisms are poorly ...
Xiao Wei, Hong‐Ping Wen, Jian‐Bo Song, Jin‐Fang Xu, Hong‐Rui Guo   +4 more
wiley   +1 more source

Hexapod Locomotion Across Structured and Unstructured Terrains: A Data‐Driven Review of Modeling, Control, and Validation

Journal of Field Robotics, EarlyView.
ABSTRACT The design of a hexapod is complex and requires integration between kinematic models, control systems, and sensing. Existing literature has reviewed these sub‐systems in isolation. Since 2021, there has been no review of the field despite significant advancements in soft soil, lunar traversal, and artificial intelligence.
Akhil Rampersad, Bashan Naidoo
wiley   +1 more source

Concentration-QTcF analysis of quizartinib in patients with newly diagnosed FLT3-internal-tandem-duplication-positive acute myeloid leukemia. [PDF]

Clin Transl Sci
Vaddady P, Smania G, Nakayama S, Inoue H, Kurumaddali A, Abutarif M, Zheng M.   +6 more
europepmc   +1 more source

Innovations in Printed Transparent Conducting Electrodes for Advanced Next‐Generation Electronics: A Comprehensive Review

Small, EarlyView.
This review highlights advances in transparent conducting electrodes for flexible wearable electronics, analyzing their optical, electrical, and mechanical properties and their prospects for sustainable, next‐generation energy devices. ABSTRACT The emergence of wearable electronics has revolutionized photophysical and electrochemical, enabling ...
Vinayak Vitthal Satale, Sourav Acharya, Keum‐Jin Ko, Sagnik Chowdhury, Danya Srinivasan, Abrar Karim, Jae‐Wook Kang   +6 more
wiley   +1 more source

Genomic Characterization of Partial Tandem Duplication Involving the KMT2A Gene in Adult Acute Myeloid Leukemia. [PDF]

Cancers (Basel)
Seto A, Downs G, King O, Salehi-Rad S, Baptista A, Chin K, Grenier S, Nwachukwu B, Tierens A, Minden MD, Smith AC, Capo-Chichi JM.   +11 more
europepmc   +1 more source

Baselining Large Language Model Performance in Systems Engineering Using SysEngBench

Systems Engineering, EarlyView.
ABSTRACT In the rapidly evolving field of artificial intelligence (AI), large language model s (LLMs) have demonstrated impressive capabilities in generating natural language. However, their proficiency in specialized domains, particularly in the field of systems engineering (SE), remains less explored and unquantified.
Ryan Bell, Ryan Longshore, Raymond Madachy, Ashlyn Hanrahan   +3 more
wiley   +1 more source

Detection of KMT2A Partial Tandem Duplication by Optical Genome Mapping in Myeloid Neoplasms: Associated Cytogenetics, Gene Mutations, Treatment Responses, and Patient Outcomes. [PDF]

Cancers (Basel)
Wei Q, Hu S, Xu J, Loghavi S, Daver N, Toruner GA, Wang W, Medeiros LJ, Tang G.   +8 more
europepmc   +1 more source

Variation on Toxic and Inflammatory Potential of Coal Smoke of Different Sources From a Region With High Lung Cancer Risk

Environmental Toxicology, EarlyView.
ABSTRACT Excess lung cancer risk in Xuanwei and Fuyuan, China, has been attributed to household air pollution from use of a locally sourced smoky (bituminous) coal. However, the carcinogenic mechanisms remain unclear. Given the important role of inflammation in lung cancer development, this study compared the proinflammatory potentials of the ...
Yongliang Zhang, Wei Hu, Nathanial Rothman, Dingyu Liu, Jihua Li, Jun Xu, Bofu Ning, Roel Vermeulen, Qing Lan, Flemming R. Cassee, George S. Downward   +10 more
wiley   +1 more source

Homozygous, Intragenic Tandem Duplication of <i>SFTPB</i> Causes Neonatal Respiratory Failure. [PDF]

Am J Respir Cell Mol Biol
Wambach JA, Wegner DJ, Kitzmiller J, White FV, Heins HB, Yang P, Paul AJ, Granadillo JL, Eghtesady P, Kuklinski C, Turner T, Fairman K, Stone K, Wilson T, Breman A, Smith J, Schroeder MC, Neidich JA, Whitsett JA, Cole FS.   +19 more
europepmc   +1 more source

Establishment of a Human Cell‐Based In Vitro Test System for Investigating and Evaluating Cytotoxic and Immunomodulatory Effects of Indoor Mold

Environmental Toxicology, EarlyView.
ABSTRACT Mold growth in damp indoor environments is a widespread problem associated with respiratory health effects, though causal mechanisms remain incompletely understood. We established a human cell‐based in vitro test system using bronchial epithelial cells (NuLi‐1) and macrophages (THP‐1) to assess inhalation toxicity and immunomodulatory effects ...
Anja Wolff, Jessica Reinert, Silke Steinborn, Marion Berger, Judith Neuhoff, Lennart Marske, Kerttu Valtanen, Udo Jäckel, Stefanie Klar   +8 more
wiley   +1 more source