A Phosphorylation‐Induced Micellization Switch in the Low‐Complexity Domain of TDP‐43
Phosphorylation of TAR DNA‐binding protein's 43 kDa (TDP‐43) low‐complexity domain by casein kinase 1 delta (CK1δ) acts as a molecular switch, redirecting its self‐assembly from macroscopic phase separation toward finite‐sized, spherical block‐copolymer micelles of ∼30 nm.
Rodrigo F. Dillenburg +16 more
wiley +1 more source
Gas Loss Compensation Method for Prolonged Exposure Samples from Deep Boreholes: Experiment, Theory, and Numerical Simulation. [PDF]
Shi G +6 more
europepmc +1 more source
A bio‐inspired bidirectional‐winding origami platform enables scalable and programmable deployable structures. Double axial folding inspired by earwig hindwings and Flasher‐based hybridization create modular multilayer architectures with diverse attainable winding angles under fixed boundary conditions.
Wenyao Zhang +5 more
wiley +1 more source
Multi-Tier Validation of a Single-Lead Wearable ECG Signal-Processing Pipeline: Clinical Comparison and Algorithmic Benchmarking on Public Expert-Annotated Databases. [PDF]
Vrdoljak J, Racz DA.
europepmc +1 more source
A Unifying Thermodynamic Model for Phase Separation and Aging of Biopolymers
Phase separation and aging of intrinsically disordered proteins are placed in a unifying framework. A thermodynamically consistent time‐dependent version of associating‐polymer theory shows how the processes are intricately coupled. Assuming aging to occur through interacting sites resulting from reversible conformational transitions, the model ...
Jasper J. Michels +2 more
wiley +1 more source
Quaternionic response geometry for proteins: toward a noncommutative theory of ordered deformations. [PDF]
Chen X +8 more
europepmc +1 more source
From Folding Mechanics to Robotic Function: A Unified Modeling Framework for Compliant Origami
A geometry‐consistent DDG framework captures compliant origami deformation from rigid‐like folding to soft panel bending. By tuning crease and panel stiffness, bistable snap‐through responses transform into smooth monostable deformation, enabling programmable stability and robot‐scale locomotion.
Bohan Zhang +7 more
wiley +1 more source
An exploratory dosimetric and treatment-time analysis of tangent-arc and continuous semi-arc VMAT in deep inspiration breath-hold radiotherapy for stage I left-sided breast cancer. [PDF]
Li Y +9 more
europepmc +1 more source
Pattern‐dependent etching is converted into a physical prior for intelligent reconstruction of high‐aspect‐ratio silicon structures. Combining YOLO‐Pose feature extraction with a topography network, the framework retrieves depth, sidewall angle, and scallop texture from minimal destructive observations, enabling accurate cross‐scale metrology and near ...
Shuyan He +4 more
wiley +1 more source
Lie Classification and Symmetry-Preserving Reduced-Order Modeling of Nonlinear Electrostatic MEMS. [PDF]
Versaci M, Morabito FC.
europepmc +1 more source

