Optimizing Distributions for Associated Entropic Vectors via Generative Convolutional Neural Networks. [PDF]
Zhang S, Liu N, Kang W, Permuter H.
europepmc +1 more source
Drug Product Development of Lipid Nanoparticle‐Based mRNA Therapeutics and Vaccines
Overview of the development path from an mRNA–lipid nanoparticle (LNP) concept to a licensed drug product, covering LNP design, manufacturing process development, formulation, and analytical characterization. ABSTRACT Lipid nanoparticles (LNP) are currently the most relevant non‐viral delivery systems for mRNA and occasionally for smaller nucleic acids
Gideon Kersten +4 more
wiley +1 more source
Engineering oriented shape optimization of GHT-Bézier developable surfaces using a meta heuristic approach with CAD/CAM applications. [PDF]
BiBi S +6 more
europepmc +1 more source
Multiple Reconnection X‐Lines at the Earth's Magnetopause in the Presence of Magnetosheath Flow
Abstract Magnetic reconnection occurs continuously along long X‐lines at the Earth's magnetopause. The maximum magnetic shear model predicts the locations of these long X‐lines for a wide range of upstream solar wind conditions. One of the more perplexing observational results is that these X‐lines appear to be stationary, even in the presence of ...
S. A. Fuselier +9 more
wiley +1 more source
Data-driven optimization of maskless grayscale laser lithography. [PDF]
Lutey AHA +8 more
europepmc +1 more source
The Constraint of Crewed Mars Missions Based on Current Radiation Dose Measurements
Abstract Crewed missions to Mars will be a milestone of future space exploration programs. However, the absence of Earth's magnetic field leaves astronauts directly exposed to unattenuated energetic particles in deep space, primarily galactic cosmic rays (GCRs), resulting in significantly higher radiation levels and enhanced health risks. Understanding
Chao Zhang +4 more
wiley +1 more source
TANGO: Analysis and curation of particles in cryo-electron tomography. [PDF]
Schreiber M, Turoňová B.
europepmc +1 more source
Kinetic Structure of an Interplanetary Shock Observed at Two Heliocentric Longitudes
Abstract Collisionless shocks convert bulk flow energy into heat, electromagnetic fields, and non‐thermal particle populations. Recent studies suggest that downstream magnetic oscillations could play an important role in ion‐scale energy dissipation at low‐Mach‐number shocks; however, the specific shock and plasma parameters involved remain poorly ...
J. J. Boldú +12 more
wiley +1 more source
NeuroDecon: A Neural Network-Based Method for Three-Dimensional Deconvolution of Fluorescent Microscopic Images. [PDF]
Sachuk A +4 more
europepmc +1 more source
A characterisation of snowflakes via rectifiability
Abstract We prove a generalisation to every metric space of Tyson–Wu's characterisation of metric spaces biLipschitz equivalent to snowflakes, by removing compactness, doubling and embeddability assumptions. We also characterise metric spaces that are biLipschitz equivalent to a snowflake in terms of the absence of non‐trivial metric 1‐currents in ...
Emanuele Caputo, Nicola Cavallucci
wiley +1 more source

