Results 221 to 230 of about 36,624 (293)

Fouling‐Free Inertial Microfluidic Cell Clarification for Lentivirus Manufacturing

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Lentiviral vectors (LVVs) are widely used as gene‐delivery vehicles in cell and gene therapy, enabling stable integration of transgenes into target cells. However, efficient clarification of LVV harvest remains a major bottleneck in large‐scale manufacturing, as conventional depth filtration often results in significant product loss.
Dohyun Park, Alexander Bevacqua, Mingyang Cui, Marina Nichols, Jianzhu Chen, Jongyoon Han   +5 more
wiley   +1 more source

On manifolds with almost non-negative Ricci curvature and integrally-positive k th -scalar curvature. [PDF]

Math Ann
Cucinotta A, Mondino A.
europepmc   +1 more source

Glycoengineered Recombinant Alpha1‐Antitrypsin Results in Comparable In Vitro and In Vivo Activities to Human Plasma‐Derived Protein

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Alpha‐1‐antitrypsin (A1AT) is a multifunctional, clinically important, high‐value therapeutic glycoprotein that can be used for the treatment of many diseases, such as A1AT deficiency, diabetes, graft‐versus‐host disease, cystic fibrosis, and various viral infections. Currently, the only U.S. food and drug administration‐approved treatment for
Frances Rocamora, Chen‐Lin Hsieh, Sanne Schoffelen, Johnny Arnsdorf, Eric A. Toth, Abdul S. Yunus, Thomas E. Cleveland IV, Sara Petersen Bjørn, Mina Ying Min Wu, Noel G. McElvaney, Bjørn Gunnar Rude Voldborg, Thomas R. Fuerst, Nathan E. Lewis   +12 more
wiley   +1 more source

Geometric and singularities insights of swept surfaces via the Bishop frame in Euclidean 3-Space. [PDF]

PLoS One
Mofarreh F, Abdel-Baky R, Alsahli M.
europepmc   +1 more source

Translating Blue Light Stimulation From Batch to Perfusion: Process and Intracellular Metabolic Analysis

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Improving cell‐specific productivity remains a central objective in biopharmaceutical manufacturing. In this study, the effect of blue light illumination on IgG1‐producing CHO DP‐12 cells was systematically evaluated across batch, fed‐batch, and perfusion cultivations in controlled 3 L bioreactor systems.
Stefanie Föller, Attila Teleki, Ralf Takors   +2 more
wiley   +1 more source

Radiographic Posterior Tibial Slope Measurement in Medial Unicompartmental Knee Arthroplasty: A Retrospective Validation Study Using Digital Volume Tomography of Tibial Resectates. [PDF]

J Clin Med
Tsimopoulos D, Ostheim P, Kaiser M.
europepmc   +1 more source

An Indicator‐Based Decision Framework for Circular Bioeconomy Transition in the Steel Industry: Integrating Multiphase Learning and Cooperative Game Modelling

Business Strategy and the Environment, EarlyView.
ABSTRACT Despite growing attention to the circular bioeconomy (CBE), the steel industry currently lacks a standardised, sectoral measurement framework to facilitate a low‐carbon transition. In this study, a decision‐support framework for evaluating CBE performance in the steel industry is proposed.
Ali Zamani Babgohari, Mohammadreza Sadeghi‐Moghadam, Hannan Amoozad Mahdiraji   +2 more
wiley   +1 more source

Larkin length as a criterion for antiferromagnetic writing

Khokhlov N, Buzdakov A, Gareev T, Li S, Wang X, Artyukhin S, Kimel A.   +6 more
europepmc   +1 more source

Sagittal parameters after primary TKA affecting knee joint function: a correlative analysis and predictive model construction. [PDF]

J Orthop Surg Res
Xu W, Huang X, Liu J, Zhang Z, Chen Z, Xia T, Yan B, Xu Y.   +7 more
europepmc   +1 more source

Sectoral Heterogeneity in Corporate Biodiversity Disclosure: Evidence from Chinese Listed Companies Across Industries, 2001–2023

Business Strategy and the Environment, EarlyView.
ABSTRACT This study examines sectoral heterogeneity in corporate biodiversity disclosure (CBD) among Chinese listed firms over the period 2001–2023. Drawing on stakeholder, institutional, and resource dependency theories, it investigates how environmental exposure, ownership structures, and market dynamics influence biodiversity risk recognition and ...
Orkun Bayram, Irmak Aksoy, Yavuz Selim Balcıoğlu   +2 more
wiley   +1 more source