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Many targeted therapies are administered at or near the maximum tolerated dose (MTD). With the advent of precision medicine, a larger therapeutic window is expected. Therefore, dose optimization will require a new approach to early clinical trial design.
Matthew J. Goldstein +3 more
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Eosinophilic peritonitis with colon cancer: a case report
Background Eosinophilic gastrointestinal disorders (EGIDs) are a rare group of inflammatory disorders that can occur anywhere along the gastrointestinal tract, from the esophagus to the rectum.
Ryo Ataka +11 more
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Microphysiological systems provide the opportunity to model accelerated changes at the human tissue level in the extreme space environment. Spaceflight-induced muscle atrophy experienced by astronauts shares similar physiological changes to muscle ...
Maddalena Parafati +16 more
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Expanding the chemical diversity of M13 bacteriophage
Bacteriophage M13 virions are very stable nanoparticles that can be modified by chemical and genetic methods. The capsid proteins can be functionalized in a variety of chemical reactions without loss of particle integrity.
Grace L. Allen +6 more
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The ‘Tango of Argentina and Uruguay’ was inscribed in the List of Intangible Cultural Heritage of UNESCO in 2009 to be safeguarded as one of humanity’s outstanding cultural achievements. Controversies and shortcomings related to the inscription have been
Nóra Kovács
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Geraniums (pelargoniums or storksbills, officially named as Pelargonium zonale (L.) L'Hér. Ex Aiton) are appreciated worldwide due to their ornamental potential and versatility.
Andreea MOLDOVAN +4 more
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Article explaining tango as a musical genre.
Aggelos Lazaris +6 more
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Argentine tango in the rehabilitation of patients with Parkinson’s disease [PDF]
Parkinson’s disease (PD) is a progressive, neurodegenerative disease leading to disability. Parkinson’s disease causes the occurrence of movement disorders, such as bradykinesia, hipokinesia, rigidity, tremor, postural instability, gait disorders and ...
Joanna Stożek +2 more
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Tango therapy for Parkinson's disease: Effects of rush elemental tango therapy
Tango therapy is very effective by applying tango elements according to the clinical severity and status of a patient. Maximization of the clinical effects of tango therapy in patients with Parkinson's disease may be achieved by the proper prescription ...
Youngsoon Koh, Geunwoong Noh
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Borges y el tango, una revisión
En Borges hay una la relación estrecha con el tango. Su visión de esta música se relaciona con las experiencias que tuvo en medio del auge y la difusión inicial de este género de la música argentina.
Néstor Espitia Cabrejo +1 more
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