Results 221 to 230 of about 26,610 (275)

Dynamic, Unconstrained Optimization of Secreted Enzyme Production in Fed‐Batch Fermentation Using Reinforcement Learning

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT Reinforcement learning (RL) has been used to control a wide range of dynamic processes, especially ones that are too complex to model well or have stochastic environmental perturbations. Fed‐batch fermentations are subject to changes in starting cell growth rates and process variations that can affect cell growth and secreted target production.
Sai Harish Uthravalli   +3 more
wiley   +1 more source

Reprogramming tumor immune microenvironment by ultrasound‐responsive nanoplatforms for enhanced cancer immunotherapy

open access: yesBMEMat, EarlyView.
Ultrasound‐responsive nanoplatforms reprogram the tumor immune microenvironment by targeting tumor cells, immune cells, and non‐immune stromal cells to enhance the efficacy of cancer immunotherapy. Abstract Cancer immunotherapy represents a significant advancement in cancer treatment by enhancing the specific recognition and elimination of cancer cells.
Shilong Zhao   +4 more
wiley   +1 more source

Tetraspanin‐ESCRT sorting drives miR‐29b packaging into extracellular vesicles to reverse fibrosis in intrauterine adhesions

open access: yesBMEMat, EarlyView.
MiR‐29b is enriched in extracellular vesicles (EVs) via a tetraspanin transporter‐dependent endocytosis and sorting complex required for the endosomal transport (ESCRT)‐dependent pathway. These EVs target the 3′ untranslated region (3′UTR) of TGFB2, thereby inhibiting the TGF‐β/Smad3 signaling pathway and repairing endometrial damage in intrauterine ...
Lihao Chen   +10 more
wiley   +1 more source

Elemental composition of vaping and smoking aerosols: Influence of liquid type and tank conditions. [PDF]

open access: yesPLoS One
Chwał J   +5 more
europepmc   +1 more source

A neuro‐behavioural model of neophobia

open access: yesBiological Reviews, EarlyView.
ABSTRACT Fear can be defined as the internal neurological state that releases a repertoire of behaviours an animal performs to reduce the effect of an aversive factor. Neophobia, the fear of novelty, is a fundamental behavioural trait observed across a wide range of species from arthropods to humans.
Arik Dorfman, Aziz Subach, Inon Scharf
wiley   +1 more source

Advances in causal discovery methods for ecological time series

open access: yesBiological Reviews, EarlyView.
ABSTRACT Recent advances in data collection technologies (e.g. automated sensor networks, satellite remote sensing, and high‐throughput sequencing) have greatly expanded the availability of ecological time series, enabling new opportunities for causal analyses in dynamic ecosystems.
Kenta Suzuki   +6 more
wiley   +1 more source

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