Results 101 to 110 of about 1,493,646 (317)

Nano‐Enabled Systemic Delivery of STING Agonist by Engineered Silicasome for Potent Antitumor Immunotherapy

open access: yesAdvanced Science, EarlyView.
Engineered mesoporous silica nanoparticles (Silicasomes) enable systemic delivery of the STING agonist ADU‐S100, overcoming the instability and toxicity that limit cyclic dinucleotides to local administration. By enhancing tumor accumulation, activating systemic antitumor immunity, and remodeling the tumor immune microenvironment, these nanoparticles ...
Wenjing Zhou   +10 more
wiley   +1 more source

Fluid–Solid Mixing Transfer Mechanism and Flow Patterns of the Double-Layered Impeller Stirring Tank by the CFD-DEM Method

open access: yesEnergies
The optimization design of the double-layered material tank is essential to improve the material mixing efficiency and quality in chemical engineering and lithium battery production.
Man Ge, Gaoan Zheng
doaj   +1 more source

Project OASIS: Optimizing Aquaponic Systems to Improve Sustainability [PDF]

open access: yes, 2016
Started in Fall 2015, Project OASIS (Optimizing Aquaponic Systems to Improve Sustainability) is an interdisciplinary capstone project with the goal of designing a sustainable and affordable small-scale aquaponic system for use in developing nations to ...
Balcom, Paige, Nigam, Siddharth
core   +1 more source

Gasdermin D‐Mediated Release of IL‐33 Results in Fetal Brain Developmental Abnormalities During Maternal Colitis

open access: yesAdvanced Science, EarlyView.
Under colitis, Gsdmd mediates the release of IL‐33 from the epithelium of pregnant mice. IL‐33 can cross the placenta and enhance the proliferative capacity of neural stem cells, ultimately resulting in behavioral deficits in the offspring. Excessive pyroptosis in the colonic epithelium also triggers the translocation of LPS, which in turn increases ...
Huiyang Jia   +4 more
wiley   +1 more source

Low Gravity Issues of Deep Space Refueling [PDF]

open access: yes
This paper discusses the technologies required to develop deep space refueling of cryogenic propellants and low cost flight experiments to develop them.
Anon   +12 more
core   +2 more sources

Design parameters comparison of bubble column, airlift and stirred tank photobioreactors for microalgae production

open access: yesBioprocess and biosystems engineering (Print)
Microalgae are the most propitious feedstock for biofuel production due to their lipid and fatty acid content. Microalgae cultivation shares many features with bioreactors, such as thermal and pH regulation, feeding procedures, and mixing to enhance heat
Başar Uyar   +2 more
semanticscholar   +1 more source

A Dynamic 3D Human Liver Sinusoid Model for Mechanistic Interrogation of Fontan‐Associated Liver Disease

open access: yesAdvanced Science, EarlyView.
This study presents a perfusable 3D bioengineered liver sinusoid platform that integrates biofabrication, 3D cell culture, controlled hemodynamics, and multiparametric characterization to model Fontan‐associated liver disease. By decoupling pressure and hypoxia effects, the system reveals early mechanobiological and profibrotic responses under ...
Sarah Rezapourdamanab   +14 more
wiley   +1 more source

Investigation of thermal regimes of lakes used for water supply and examination of drinking water system in Kotzebue, Alaska [PDF]

open access: yes, 2012
Thesis (M.S.) University of Alaska Fairbanks, 2012Many villages in Arctic Alaska rely on lakes for water supply, such as the Alaskan City of Kotzebue, and these lakes may be sensitive to climate variability and change, particularly thermal regimes and ...
Bendlova, Tereza
core  

Nernstian Diagnostics of Imperfect Selectivity in Naphthalene Diimide‐Based Aqueous Organic Redox Flow Battery

open access: yesAdvanced Science, EarlyView.
Non‐ideal redox electrolytes still govern the Nernstian behavior of electrode potentials in aqueous organic redox flow batteries under operation. We utilized this effect to analytically predict two scenarios of battery performance degradation. ABSTRACT Aqueous organic redox flow batteries (AORFBs) enhance the sustainability of battery energy storage ...
Faudillah Alhumairah   +9 more
wiley   +1 more source

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