Results 221 to 230 of about 651,900 (282)

Baicalin Induces Ferroptosis in Breast Cancer Through a Novel STAT3/HO‐1/GPX4 Regulatory Axis

Phytotherapy Research, EarlyView.
BA inhibits STAT3 phosphorylation and activation in BC cells, accompanied by decreased expression of HO‐1 and GPX4. Reduced GPX4 activity impairs lipid peroxide clearance, promoting ROS accumulation and lipid peroxidation, which ultimately triggers ferroptosis and inhibits cell proliferation.
Tingting Guo, Fansu Meng, Detang Li, Maciej Mazur, Alicia Marcelina Díaz García, Mulazim Hussain Asim, Zhong Chen, Yiqi Chen, Yixuan Lin, Zhenjiang Yang, Panpan Wang, Yu Cai   +11 more
wiley   +1 more source

Autonomic effects and ablation success after pulsed field and cryoballoon ablation: a SINGLE SHOT CHAMPION substudy. [PDF]

Europace
Roten L, Kueffer T, Badertscher P, Jüni P, Knecht S, Thalmann G, Kozhuharov N, Krisai P, Iqbal SUR, Jufer C, Maurhofer J, Heg D, Pereira TV, Mahfoud F, Servatius H, Tanner H, Kühne M, Sticherling C, Reichlin T.   +18 more
europepmc   +1 more source

Tangeretin Targets Macrophage M1 Polarization to Alleviate Liver Injury in a Murine Model of Hepatic Sinusoidal Obstruction Syndrome

Phytotherapy Research, EarlyView.
Tangeretin (TAN) alleviates monocrotaline‐induced hepatic sinusoidal obstruction syndrome in mice. By attenuating the Keap1–Nrf2 interaction, TAN promotes Nrf2 nuclear translocation and mitophagy, thereby preserving mitochondrial homeostasis and reducing mitochondrial reactive oxygen species.
Fumin Zhang, Cheng Zhu, Xingyu Li, Tianyin Sun, Yongkang Zhang, Mengwei Wu, Qianqian Zhang, Ying Dai, Xuecan Mei, Derun Kong   +9 more
wiley   +1 more source

Diastolic contributors in cardiomyocytes of a cardiometabolic HFpEF-like mouse model. [PDF]

J Gen Physiol
Shahid A, McMillen TS, Daugherty S, Burns AE, van den Berg M, Regnier M, Granzier H, Methawasin M.   +7 more
europepmc   +1 more source

Cinnamic Acid Attenuates Ethanol‐Exacerbated Hepatocyte Pyroptosis in Type 2 Diabetes via AMPK‐Mediated NLRP3/GSDMD Inhibition

Phytotherapy Research, EarlyView.
CA directly binds to and activates AMPK to suppress NLRP3/GSDMD signaling, thereby alleviating hepatocyte pyroptosis in T2DM mice. ABSTRACT Type 2 diabetes mellitus (T2DM) is frequently accompanied by chronic ethanol (ET) consumption, which worsens metabolic dysregulation and organ damage.
Huaiying Tang, Qin Xiang, Yue Zhang, Yu Zhang, Xiangxiang Fu, Liming Tan, Yongli Zhang, Siqi Li, Dong Gong, Xu Guo, Yonghong Zhang, Li Chen, Tao Zheng, Qibin Wang   +13 more
wiley   +1 more source

Pubertal development and risks of eating disorders and muscle dysmorphia in adolescents: a Danish population-based follow-up study

Thomsen AML, Ernst A, Strandberg-Larsen K, Rask CU, Gaml-Sørensen A, Benson TE, Arah OA, Ramlau-Hansen CH.   +7 more
europepmc   +1 more source

Per- and Polyfluoroalkyl Substance Exposure Associated with Later Puberty in Norwegian Girls: Data from the Bergen Growth Study 2. [PDF]

Environ Health (Wash)
Forthun IH, Roelants M, Knutsen HK, Haug LS, Iszatt N, Schell LM, Jugessur A, Viste K, Bjerknes R, Bruserud IS, Juliusson PB.   +10 more
europepmc   +1 more source

New views of some invariants associated with the Cartesian 2D velocity gradient tensor

Quarterly Journal of the Royal Meteorological Society, EarlyView.
Vorticity and divergence of horizontal flow are fundamental quantities in meteorology; both are linear functions of the four elements of the 2D velocity gradient tensor and both are formally unchanged under coordinate rotation. We explore four quadratic functions of the elements that are geometrically invariant in this sense, finding some novel ...
I. Roulstone, S. A. Clough, A. A. White
wiley   +1 more source

Letter from Elmer Tanner, Camp Sherman, Ohio, to Mother, Geneva, Ohio, November 18, 1917

, 1917
Tanner, Elmer
core  

Three Spirometry‐Based At‐Risk Phenotypes Predict Incident Airflow Limitation: A Population‐Based Study

Respirology, EarlyView.
Analysing the population‐based KORA and SHIP studies, three spirometric at‐risk subtypes (early airflow limitation, PRISm, and small airway dysfunction) were consistently associated with incident airflow limitation. Their combination in a conceptual framework identified most future cases with high negative predictive value, suggesting potential for ...
Hendrik Pott, Roman Martin, Wilhelm Bertrams, Mustafa Abdo, Margit Heier, Annette Peters, Beate Stubbe, Max Kutzinski, Anne Obst, Ralf Ewert, Dominik Heider, Henry Völzke, Gernot Rohde, Claus F. Vogelmeier, Bernd Schmeck, Stefan Karrasch, on behalf of the KORA‐study group   +16 more
wiley   +1 more source