Results 51 to 60 of about 613,644 (396)

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

Tapping the tree-ring archive for studying effects of resin extraction on the growth and climate sensitivity of Scots pine

open access: yesForest Ecosystems, 2017
BackgroundIn the German Democratic Republic (GDR), resin tapping in Scots pine (Pinus sylvestris L.) forests was a major economic activity, and resin-tapped stands are frequently found up until this day.
E. van der Maaten   +3 more
semanticscholar   +1 more source

Evaluation of low frequency tapping systems with stimulation on hevea in traditional area Cambodia [PDF]

open access: yes, 2019
In Cambodia, the common tapping system which was widely adopted by smallholders and agro-industry plantations was S/2 d3 for downward tapping and S/4 d3 for upward tapping.
Chan, C.   +4 more
core  

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

open access: yesFEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

A Validation Study of a Smartphone-Based Finger Tapping Application for Quantitative Assessment of Bradykinesia in Parkinson’s Disease

open access: yesPLoS ONE, 2016
Background Most studies of smartphone-based assessments of motor symptoms in Parkinson’s disease (PD) focused on gait, tremor or speech. Studies evaluating bradykinesia using wearable sensors are limited by a small cohort size and study design.
Chae Young Lee   +5 more
semanticscholar   +1 more source

Physics of beer tapping

open access: yes, 2014
The popular bar prank known in colloquial English as beer tapping consists in hitting the top of a beer bottle with a solid object, usually another bottle, to trigger the foaming over of the former within a few seconds.
Casado-Chacon, Almudena   +2 more
core   +1 more source

Performances of low frequency rubber tapping system with rainguard in high rainfall area in Myanmar [PDF]

open access: yes, 2017
In Myanmar, natural rubber (Hevea brasiliensis) is mainly grown in the southern part of the country, where the rainfall is too high leading to suspension of tapping in the rainy season and intensive tapping after the rainy season.
Lacote, Régis   +2 more
core   +1 more source

Higher Amyloid and Tau Burden Is Associated With Faster Decline on a Digital Cognitive Test

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective A 2‐min digital clock‐drawing test (DCTclock) captures more granular features of the clock‐drawing process than the pencil‐and‐paper clock‐drawing test, revealing more subtle deficits at the preclinical stage of Alzheimer's disease (AD). A previous cross‐sectional study demonstrated that worse DCTclock performance was associated with
Jessie Fanglu Fu   +16 more
wiley   +1 more source

Harry Potter and the Glottal Stop: Glottal Replacement and T-Voicing in Contemporary RP [PDF]

open access: yesFilolog, 2018
The aim of this paper is to highlight the extent of advance made by T-glottalling and T-voicing in younger RP (Received Pronunciation) speakers. The scope of the research extends no further than two speakers, actors Daniel Radcliffe and Emma Watson, with
Andrej Ž. Bjelaković
doaj   +1 more source

Characterization of the potential yield of clone IRCA230 [PDF]

open access: yes, 2014
The experiment on Yield Potential Comparison on S/2 d3 and S/2d4 Tapping Systems of Clones IRCA230 were practiced on farm research at Chup Rubber Research Station of Cambodian Rubber Research Institute (CRRI). The experimental design was the RCBD with 8
Chhek, Chan   +3 more
core  

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