Characterisation of the Na, K pump current in atrial cells from patients with and without chronic atrial fibrillation [PDF]
<b>Objective:</b> To assess the contribution of the Na, K pump current (<i>I</i><sub>p</sub>) to the action potential duration (APD) and effective refractory period (ERP) in human atrial cells, and to investigate ...
Kane, K.A. +5 more
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Catheter ablation of atrial fibrillation : radiofrequency catheter ablation for redo procedures after cryoablation [PDF]
Aim: To evaluate the effectiveness of two different strategies using radiofrequency catheter ablation for redo procedures after cryoablation of atrial fibrillation. Methods: Thirty patients (paroxysmal atrial fibrillation: 22 patients, persistent atrial
Gramley, Felix, Kettering, Klaus
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Mechanisms of termination and prevention of atrial fibrillation by drug therapy [PDF]
Atrial fibrillation (AF) is a disorder of the rhythm of electrical activation of the cardiac atria. It is the most common cardiac arrhythmia, has multiple aetiologies, and increases the risk of death from stroke.
Smith, G.L. +5 more
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Managing atrial fibrillation in the global community: The European perspective. [PDF]
Atrial fibrillation is a common, global problem, with great personal, economic and social burdens. As populations age it increases in prevalence and becomes another condition that requires careful chronic management to ensure its effects are minimised ...
Kaba, RA +3 more
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Amplatzer device closure of an inferior venosus atrial septal defect after surgical closure of a secundum atrial septal defect [PDF]
This article presents a patient who had transcatheter closure of a low atrial septal defect which was overlooked during surgical closure of a secundum atrial septal defect.
DeGiovanni, Joseph V. +2 more
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Cardiac adrenergic control and atrial fibrillation [PDF]
Atrial fibrillation (AF) is the most common cardiac arrhythmia, and it causes substantial mortality. The autonomic nervous system, and particularly the adrenergic/cholinergic balance, has a profound influence on the occurrence of AF ...
Workman, A.J.
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Fibrilaçao atrial durante taquicardia por reentrada nodal atrioventricular: achado sugestivo da presença de via superior comum nodal [PDF]
Na taquicardia por reentrada nodal atrioventricular, a necessidade do átrio para a manutençao da taquicardia é controverso. Descrevemos um caso de fibrilaçao atrial ocorrendo durante taquicardia por reentrada nodal atrioventricular sem afetar o ciclo da ...
Rafael de March Ronsoni +3 more
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Ionic basis of a differential effect of adenosine on refractoriness in rabbit AV nodal and atrial isolated myocytes [PDF]
Methods: The whole cell patch clamp technique was used to record action potentials and ion currents in AV nodal and left atrial myocytes isolated enzymatically from rabbit hearts.
Kane, K.A., Rankin, A.C., Workman, A.J.
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A preliminary assessment of the effects of ATI-2042 in subjects with paroxysmal atrial fibrillation using implanted pacemaker methodology [PDF]
Aims ATI-2042 (budiodarone) is a chemical analogue of amiodarone with a half life of 7 h. It is electrophysiologically similar to amiodarone, but may not have metabolic and interaction side effects.
Camm, AJ +5 more
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HL-1 cells express an inwardly rectifying K+ current activated via muscarinic receptors comparable to that in mouse atrial myocytes [PDF]
An inwardly rectifying K^+ current is present in atrial cardiac myocytes that is activated by acetylcholine (I_{KACh}). Physiologically, activation of the current in the SA node is important in slowing the heart rate with increased parasympathetic tone ...
Muriel Nobles +6 more
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