Results 51 to 60 of about 1,387,158 (290)

CPX‐351 in High‐Risk Relapsed Pediatric Acute Leukemia: Real‐World Phase 1 Data Establishing the FDA‐Approved Dose

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background/Objectives Outcomes for pediatric relapsed/refractory (R/R) acute myeloid leukemia (AML) remain dismal. CPX‐351, a liposomal formulation of cytarabine and daunorubicin, may have less off‐target toxicities than traditional chemotherapies and has shown improved outcomes for adults with newly diagnosed therapy‐related AML.
Jonathan D. Bender   +17 more
wiley   +1 more source

ACCase-inhibiting herbicides: mechanism of action, resistance evolution and stewardship

open access: yesScientia Agricola, 2020
Herbicides play an important role in preventing crop yield losses due to both their weed interference ability and their capacity for increasing soil conservation in no-till systems.
Hudson Kagueyama Takano   +4 more
doaj   +1 more source

Non-Target Site Resistance in Summer-Emerging Lolium rigidum and the Effect of Alternative Herbicides

open access: yesAgronomy, 2023
Herbicide resistance is an important weed management issue. Glyphosate is the most dominant herbicide, which controls a broad spectrum of weeds, including grasses such as Lolium rigidum. Lolium rigidum is a major weed of winter crops in Australia that is
Michael Thompson, Bhagirath S. Chauhan
doaj   +1 more source

Physiological and Molecular Characterization of Hydroxyphenylpyruvate Dioxygenase (HPPD)-inhibitor Resistance in Palmer Amaranth (Amaranthus palmeri S. Wats.) [PDF]

open access: yes, 2017
Citation: Nakka, S., Godar, A. S., Wani, P. S., Thompson, C. R., Peterson, D. E., Roelofs, J., & Jugulam, M. (2017). Physiological and Molecular Characterization of Hydroxyphenylpyruvate Dioxygenase (HPPD)-inhibitor Resistance in Palmer Amaranth ...
Godar, A. S.   +6 more
core   +1 more source

Upacicalcet: A Novel Intravenous Calcimimetic Agent for Patients Undergoing Hemodialysis With Secondary Hyperparathyroidism

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Secondary hyperparathyroidism (SHPT) is a common complication in patients receiving maintenance dialysis, driven by calcium and phosphate metabolism disturbances. Calcimimetics are central to the management of SHPT by enhancing calcium‐sensing receptor sensitivity and reducing parathyroid hormone secretion.
Fumihiko Koiwa   +3 more
wiley   +1 more source

Is hormesis an underestimated factor in the development of herbicide resistance?

open access: yesJulius-Kühn-Archiv, 2014
The growing impact of herbicide resistant weeds increasingly affects weed management and the delay of resistance evolution has become a major task of chemical weed control.
Belz, Regina G.
doaj   +1 more source

Entwicklung der Herbizidresistenz bei Acker-Fuchsschwanz (Alopecurus myosuroides) in Bayern

open access: yesJulius-Kühn-Archiv, 2020
Acker-Fuchsschwanz (Alopecurus myosuroides) ist eines der wichtigsten Leitungräser im bayerischen Ackerbau. Für die Vermeidung von hohen Ertrags- und Qualitätsverlusten ist eine effektive chemische Bekämpfung in wichtigen Ackerbaukulturen wie ...
Gehring, Klaus   +2 more
doaj   +1 more source

Identifying Current and Missing Knowledge in the Control of Pyrethroid-Resistant Triatoma Infestans, Vector of Chagas Disease [PDF]

open access: yes, 2017
Triatomines are blood-sucking bugs that occur mainly in Latin America. They are vectors of Trypanosoma cruzi, the parasite that causes Chagas disease.
Picollo, Maria Ines   +1 more
core   +1 more source

Insecticide resistance resulting from an absence of target-site gene product [PDF]

open access: yesProceedings of the National Academy of Sciences, 1998
Genetic changes in insects that lead to insecticide resistance include point mutations and up-regulation/amplification of detoxification genes. Here, we report a third mechanism, resistance caused by an absence of gene product. Mutations of the Methoprene-tolerant ( Met ) gene of ...
T G, Wilson, M, Ashok
openaire   +2 more sources

Mapping the evolution of mitochondrial complex I through structural variation

open access: yesFEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin   +2 more
wiley   +1 more source

Home - About - Disclaimer - Privacy