Results 51 to 60 of about 8,010,330 (245)

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Status and development of ACCase and ALS inhibitor resistant black-grass (Alopecurus myosuroides Huds.) in neighboring fields in Germany

open access: yesJulius-Kühn-Archiv, 2012
Neighboring fields in three local areas of southern Germany have been investigated for the infestation level and herbicide resistance structure of black-grass (Alopecurus myosuroides Huds.).
Hess, Martin   +5 more
doaj   +1 more source

Is hormesis an underestimated factor in the development of herbicide resistance?

open access: yesJulius-Kühn-Archiv, 2014
The growing impact of herbicide resistant weeds increasingly affects weed management and the delay of resistance evolution has become a major task of chemical weed control.
Belz, Regina G.
doaj   +1 more source

ACCase-inhibiting herbicides: mechanism of action, resistance evolution and stewardship

open access: yesScientia Agricola, 2020
Herbicides play an important role in preventing crop yield losses due to both their weed interference ability and their capacity for increasing soil conservation in no-till systems.
Hudson Kagueyama Takano   +4 more
doaj   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

open access: yesFEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani   +3 more
wiley   +1 more source

Herbicide Resistance and Management Options of Papaver rhoeas L. and Centaurea cyanus L. in Europe: A Review

open access: yesAgronomy, 2020
Corn poppy (Papaver rhoeas L.) and cornflower (Centaurea cyanus L.) are two overwintering weed species found in crop fields in Europe. They are characterised by a similar life cycle, similar competitive efforts, and a spectrum of herbicides recommended ...
Marta Stankiewicz-Kosyl   +11 more
doaj   +1 more source

Investigation and characterisation of diamide insecticide resistance conferred by target-site mutations in the Ryanodine Receptor of lepidopteran pests [PDF]

open access: yes, 2019
Lepidopteran crop pests such as Tuta absoluta, Chilo suppressalis, Spodoptera frugiperda and Plutella xylostella are becoming increasingly problematic, as populations colonise new regions of the globe.
Richardson, E.
core  

Alterations in life-history associated with non-target-site herbicide resistance in Alopecurus myosuroides [PDF]

open access: yes, 2019
The evolution of resistance to herbicides is a classic example of rapid contemporary adaptation in the face of a novel environmental stress. Evolutionary theory predicts that selection for resistance will be accompanied by fitness trade-offs in ...
Knight, C.   +5 more
core   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Pinoxaden resistance in Lolium perenne L. is due to both target-site and non-target-site mechanisms

open access: yes, 2022
Application of herbicides inhibiting acetyl CoA carboxylase (ACCase) has been one of the main strategies for selectively controlling grass weed species such as perennial ryegrass (Lolium perenne L.) in wheat and barley crops in New Zealand. In this study,
Hossein Ghanizadeh (9628392)   +4 more
core  

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