Results 101 to 110 of about 2,235,948 (277)

Efficient Target Classification Based on Vehicle Volume Estimation in High-Resolution Radar Systems

open access: yesRemote Sensing
In this paper, we propose a method for efficient target classification based on the spatial features of the point cloud generated by using a high-resolution radar sensor.
Sanghyeok Hwangbo   +3 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Radar Target Classification Using Enhanced Doppler Spectrograms with ResNet34_CA in Ubiquitous Radar

open access: yesRemote Sensing
Ubiquitous Radar has become an essential tool for preventing bird strikes at airports, where accurate target classification is of paramount importance. The working mode of Ubiquitous Radar, which operates in track-then-identify (TTI) mode, provides both ...
Qiang Song   +6 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

A kinetic model predicts SpCas9 activity, improves off-target classification, and reveals the physical basis of targeting fidelity. [PDF]

open access: yesNat Commun, 2022
Eslami-Mossallam B   +7 more
europepmc   +1 more source

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