Results 201 to 210 of about 2,545,393 (299)

Multi-Tissue Omics Analysis Uncovers Translational Regulation Underlying Complex Traits in Pigs. [PDF]

Adv Sci (Weinh)
Wang C, Zhang Y, Chen C, Xu X, Qin S, Qi J, Bao Y, Li H, Chen R, Zheng W, Chen Z, Fang L, Zhao Y, Liu Y.   +13 more
europepmc   +1 more source

Matrix metalloproteinase‐9 regulates cell adhesion and membrane protrusive activity of ovarian cancer cells

FEBS Open Bio, EarlyView.
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel, Sam Bennett, Natalie Ehlinger, Nelson Cook, Katelyn Marvin, Caleb L. Lines, Sam Reyes, Brooke Kirby, Shawn M. Ellerbroek   +8 more
wiley   +1 more source

Real-Time Detection and Counting Method for Distant-Water Tuna Based on Improved YOLOv10n-EMCNet. [PDF]

Sensors (Basel)
Liu Y, Zhang Z, Cheng Y, Liang H, Wan J, Wang C.   +5 more
europepmc   +1 more source

Implementation Research to Understand and Target Complex Needs: A Case Study of US-based Food Assistance Programming (P10-147-19)

Current Developments in Nutrition, 2019
Andrea Warren, Edward Frongillo, Shana Alford, Erin McDonald, Jessica Escobar-Alegria   +4 more
openaire   +1 more source

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

FEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu, Lanlan Li, Wenjuan Jia, Hanzhong Feng, Xiaoquan Yu, Youli Zhao, Fengzhi Yuan, Hui Ding, Junqiang Tian, Yong‐Xing He, Zhiping Wang   +10 more
wiley   +1 more source

SSH-YOLO: YOLOv8 improved model based on Object Detection in Complex Road Scenes. [PDF]

PLoS One
Ma T, Chen Y, Li J, Yu H, He C.
europepmc   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Observation of redistribution for local conformational dynamics in cross-reactive antibody design. [PDF]

J Biochem
Yasuda Y, Nagatoishi S, Sasaki J, Matsunaga R, Kuroda D, Hashiguchi T, Tsumoto K.   +6 more
europepmc   +1 more source

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

FEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková, Veronika Hovanová, Jiri Damborsky, Erik Sedlák   +3 more
wiley   +1 more source