Results 101 to 110 of about 143,329 (299)

A Survey on Economic-driven Evaluations of Information Technology [PDF]

open access: yes, 2007
The economic-driven evaluation of information technology (IT) has become an important instrument in the management of IT projects. Numerous approaches have been developed to quantify the costs of an IT investment and its assumed profit, to evaluate its ...
Mutschler, B.   +2 more
core   +2 more sources

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

open access: yesFEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar   +4 more
wiley   +1 more source

Re-Costing Cairo: Revised Estimate of the Resource Requirements to Achieve the ICPD Goals [PDF]

open access: yes, 2009
Achieving universal access to reproductive health, including family planning services and supplies, is essential to ensuring the health and well-being of women and their families.
Suzanna Dennis
core  

Emerging insights into CC and CXC chemokines and their receptors in Mycobacterium tuberculosis infection

open access: yesFEBS Open Bio, EarlyView.
The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Kostenkontrolle oder Controlling? Verbreitung und Effekte betriebswirtschaftlicher Planungs- und Steuerungsinstrumente in der Industrie [PDF]

open access: yes
Die Praxis der betriebswirtschaftlichen Planung und Steuerung folgt vielfach alten Kostenkontrollprinzipien. Hohe Gemeinkostenblöcke und eine mangelnde Unterstützung neuer Produktionskonzepte sind die Folge.
Kinkel, Steffen
core  

Improving the Reproductive Health of Married and Unmarried Youth in India [PDF]

open access: yes, 2006
Provides insights and lessons learned from a ten-year multi-partner research program to improve youth reproductive and sexual health in India.
Kathleen Kurz   +4 more
core  

Re‐Awakening Public Attention to the Silent Pandemic of Cancer Among Older Adults in Low‐ and Middle‐Income Countries

open access: yesAging and Cancer, EarlyView.
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef   +2 more
wiley   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

open access: yesAging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

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