Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
TARGET COSTING – THE RESPONSE OF THE MANAGERIAL ACCOUNTING TO CHANGES IN THE ENVIRONMENT [PDF]
Analele Universităţii Constantin Brâncuşi din Târgu Jiu : Seria Economie, 2014 The aim of this article is to highlight the Target Costing concept and the way in which the concept is used by the Romanian entities. The article analyzes the concept starting from the time of its appearance and up to the present moment, presenting ...
OFILEANU DIMI , BUMBESCU SORINA SIMONA
doaj
PENERAPAN METODE TARGET COSTING PADA PT. MERAK MEKAR ABADI, KALIOSO, BOYOLALI [PDF]
, 2013 Penelitian ini bertujuan untuk menerapkan metode target costing dalam upaya meningkatkan volume penjualan dengan studi kasus pada PT. Merak Mekar Abadi, Kalioso, Boyolali. Produk PT.
Vera, Yohana Tri
core
Conceptualising the impact of information asymmetry on through-life cost: case study of machine tools sector [PDF]
, 2018 Information asymmetry (IA) in terms of contextual variety and importance is one of the most challenging aspects of through-life costing in product-service systems (PSS).
Erkoyuncu, J. +6 more
core +2 more sources
Mechanisms of parasite‐mediated disruption of brain vessels
FEBS Letters, EarlyView.Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
Target costing as an element of the hard coal extraction cost planning process [PDF]
Zeszyty Teoretyczne Rachunkowości, 2017 Target costing as an element of the hard coal extraction cost planning process Striving for the efficiency of activities is of great significance in the management of hard coal extractive enterprises, which are constantly subjected to the process of ...
Katarzyna Segeth-Boniecka
doaj +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Trzy podstawowe twierdzenia Target Costing o punktach krytycznych
Polityki Europejskie, Finanse i Marketing, 2019 Celem artykułu było rozwiązanie dwóch problemów: czy dla trzech wyróżnionych punktów krytycznych czyli jednostkowego kosztu dopuszczalnego, nakładów inwestycyjnych dopuszczalnych i dopuszczalnej ceny za najnowszą technologię można sformułować twierdzenia
Jarosław Mielcarek
doaj +3 more sources
Studies on behavioral issues in target cost determination and allocation processes [PDF]
, 2000 Target costing is widely known as the system to support the cost-reduction process for reducing the price of the product at the new product development, which has been adopted not only in the automobile ...Thesis (Ph. D.
Mahmuda Akter
core
Resource Planning for Neglected Tropical Disease (NTD) Control Programs: Feasibility Study of the Tool for Integrated Planning and Costing (TIPAC). [PDF]
, 2014 Resource Planning for Neglected Tropical Disease (NTD) Control Programs: Feasibility Study of the Tool for Integrated Planning and Costing (TIPAC)
A-F Gabrielli +38 more
core +3 more sources