Results 131 to 140 of about 104,887 (271)
Advanced Science, EarlyView.A novel resistance mechanism is mediated through phagocytosis of cancer cells by AR+ TAMs. This process, dependent on ANXA2, enables macrophages to acquire AR protein from engulfed tumor cells. The internalized AR translocates into the macrophage nucleus, where it binds directly to the IL‐6 promoter, augmenting IL‐6 transcription and secretion ...
Yong Luo +13 more
wiley +1 more source
Automatic target recognition using location uncertainty
, 2000 Thesis (Ph. D.)--University of Washington, 2000In this dissertation, we present a framework for using location uncertainty information in computer vision applications.
Liu, Gang, 1970-
core
Target templates and the time course of distractor location learning
When searching for a shape target, colour distractors typically capture our attention. Capture is smaller when observers search for a fixed target that allows for a feature-specific target template compared to a varying shape singleton target. Capture is
Hanne, Aylin A. +2 more
core +1 more source
Advanced Science, EarlyView.High glucose triggers corneal endothelial dysfunction by impairing FOXO1‐mediated ITPR1 transcription, leading to disrupted mitochondria‐associated membrane (MAM) integrity and defective ER‐to‐mitochondria Ca2+ transfer. This study develops an innovative viscous DES‐AAV‐Foxo1 delivery system with enhanced transfection efficiency. This non‐invasive gene
Hongran Zhao +10 more
wiley +1 more source
Target location for autonomous helicopter
, 2007 The project is developed to accomplish the objective of locating the desired target in Level 2 of the AUVSI International Aerial Robotics Competition (lARC).
Mohite, Trupti
core
Advanced Science, EarlyView.WTAP drives cartilage regeneration by activating an LRP1‐dependent lipid metabolic program in macrophages, enhancing IL‐10 and TGF‐β secretion to promote chondrogenic differentiation. Leveraging this mechanism, virtual screening identifies LRP1‐targeting compounds that effectively stimulate cartilage repair, highlighting a druggable epigenetic ...
Chenyan Huang +6 more
wiley +1 more source
GLS1 Orchestrates Exosome‐Mediated Tumor‐Endothelial Communication to Facilitate Angiogenesis
Advanced Science, EarlyView.This study reveals a previously unappreciated, non‐metabolic function of GLS1 in the control of tumor angiogenesis via exosome‐mediated CAV1‐TNC signaling, indicating that therapeutic targeting of GLS1 may offer a dual benefit by simultaneously suppressing tumor metabolic activity and angiogenic processes in head and neck cancer. ABSTRACT Glutaminase 1
Jianqiang Yang +9 more
wiley +1 more source
APPARATUS FOR DETECTING LOCATION INFORMATION OF TARGET
, 2018 Disclosed is an apparatus for detecting location information of a target, comprising: a controller for setting the number of time slots to which a signal is transmitted, different center frequencies for each of the time slots, and an a bandwidth of the ...
이종훈, 현유진, 이철희
core
European Biodiversity Observation Network: D1.1 The Selection of Biodiversity indicators for EBONE Development Work [PDF]
, 2010 The main aim of this report is to assess which biodiversity indicators should be selected as the basis for developing new EBONE methodologies for assessing biodiversity.
Jongman, R.H.G. +3 more
core
Advanced Science, EarlyView.A self‐supervised multi‐view graph fusion framework integrates spatial multi‐omics, excelling in domain identification and denoising. It reconstructs spatial pseudo‐expression, jointly analyzes multi‐omics data, infers RNA velocity, predicts spatial omics features from single‐cell multi‐omics, and detects spatially dark genes and transcription factors,
Yuejing Lu +8 more
wiley +1 more source