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Immune mechanisms in angiotensin II-induced target-organ damage [PDF]
Inflammation and activation of immunity are central features in the pathogenesis of atherosclerosis, ischemic myocardial injury, and hypertension-induced target-organ damage.
Friedrich C Luft +2 more
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Metabolism and Target Organ Damage
Metabolism and Target Organ Damage, 2022People with diabetes mellitus (DM) undergo more elective surgery than those without DM; however, up to half of the patients are undiagnosed when referred for surgery. This is an opportunity to intervene and instigate a management plan. Preoperative strategies may vary based on coexisting medical diseases such as obesity and the availability of ...
Naomi M. Fearon, Dimitri J. Pournaras
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Obesity and target organ damage: the kidney
International Journal of Obesity, 2002Obesity is a risk marker for progressive renal function loss in patients with known renal disease. There is, however, increasing evidence that obesity may also damage the kidney in otherwise healthy subjects. There appears to be an intriguing parallel between the renal effects of obesity and those of diabetes.
de Jong, P. E. +3 more
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Hypertension and Target Organ Damage
2019The impact of arterial hypertension on the heart, the central nervous system, the arterial vessels and the kidney is responsible for subsequent mortality and morbidity. Evaluation of early target organ damage (TOD) in these organs is an important step in a risk stratification strategy to reduce cardiovascular and renal damage.
Muiesan M. L. +6 more
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Kidney in Diabetes: from Organ Damage Target to Therapeutic Target
Current Drug Metabolism, 2011Despite the growing of pharmacological options for the treatment of diabetes, epidemiological studies suggest that a substantial proportion of patients does not achieve glycemic goals and so suffers from the risk of chronic complications. This review explores the inhibition of renal glucose reabsorption as a novel approach to treat hyperglycemia ...
SALVATORE, Teresa +6 more
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Obesity and target organ damage: the heart
International Journal of Obesity, 2002In most patients, coronary atherosclerosis or congestive heart failure develop as an integrated response to multiple cardiovascular risk factors. Obesity increases the prevalence of most cardiovascular risk factors and is the predominant cause of diabetes mellitus and arterial hypertension.
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Target organ damage in acute heart failure
Revista Clínica Española (English Edition), 2016Acute heart failure is a prognostic factor due to its high mortality during the acute phase and the increased frequency of medium to long-term adverse events. The pathophysiological mechanisms triggered during these exacerbations can persist after reaching clinical stability, remaining even after the acute episode has ended.
J, Casado Cerrada +2 more
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Target Organ Damage and RAAS Blockade
2014This chapter will focus on the influence of target organ damage, particularly of left ventricular hypertrophy and subclinical kidney dysfunction, in the choice of ACEIs or ARBs therapy in patients with hypertension and heart failure.
Ilaria Spoletini +2 more
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Regression of target organ damage
Journal of Hypertension, 2013Kristian, Wachtell, Peter M, Okin
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