Object-guided contrastive language-image pre-training for zero-shot target recognition. [PDF]
Zheng C.
europepmc +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Multi-Center Prototype Feature Distribution Reconstruction for Class-Incremental SAR Target Recognition. [PDF]
Zhang K, Wu B, Li P, Kang Z, Zhang L.
europepmc +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
DT-TRAP enables accurate target recognition via simplified dosing and low-temperature incubation. [PDF]
Zhang H +7 more
europepmc +1 more source
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
An efficient transformer architecture with depthwise separable convolutions for high-accuracy underwater acoustic target recognition. [PDF]
Mahmud NA +8 more
europepmc +1 more source
Structural and biochemical analysis of a B12 superbinder
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
AlkD's Conformational Dynamics Regulated by Protein-DNA Interactions for Effective Target Recognition. [PDF]
Qi Y +7 more
europepmc +1 more source
Weighted residual network for SAR automatic target recognition with data augmentation. [PDF]
Li J, Peng C.
europepmc +1 more source

